57296-46-5

Usage

Molecular weight

255.04 g/mol

Appearance

White or off-white crystalline solid

Solubility

Soluble in polar solvents like water and ethanol

Melting point

Approximately 190-200°C

Boiling point

Not readily available, but expected to be high due to the presence of multiple functional groups

Density

Not readily available, but expected to be higher than water due to the presence of heavy chlorine atoms

Functional groups

Carboxylic acid, chlorine, and methoxy groups

Chemical structure

A benzene ring with two carboxylic acid groups at the 1 and 2 positions, two chlorine atoms at the 3 and 4 positions, and a methoxy group at the 5 position

Applications

Production of polymers and plastics with enhanced heat resistance and durability
Building block for the synthesis of pharmaceuticals and agrochemicals

Safety precautions

Harmful if it comes into contact with the skin or eyes
Use in a well-ventilated area to avoid inhalation of vapors or dust
Wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a mask when handling

Storage

Store in a cool, dry, and well-ventilated area, away from direct sunlight and heat sources

Stability

Stable under normal conditions, but may decompose upon exposure to high temperatures or strong oxidizing agents

Reactivity

Reacts with bases, reducing agents, and nucleophiles due to the presence of carboxylic acid and chlorine functional groups

Upstream product

• 54196-88-2 6,7-dichloro-2-ethyl-5-methoxy-2,3-dihydro-1H-inden-1-one 
• 27366-42-3 2-ethyl-5-hydroxy-6,7-dichloro-1-indanone 

Downstream Products

• 57296-47-6 dimethyl 3,4-dichloro-5-methoxyphthalate 
• 63001-38-7 3,4-dichloro-5-methoxybenzoyl chloride 
• 63001-46-7 3-(3,4-Dichloro-5-methoxyphenyl)propanol 
• 63001-47-8 2,3-dichloro-5-(3-bromopropyl)anisole 
• 63001-45-6 5-(3,4-dichloro-5-methoxyphenyl)valeric acid 
• 63001-43-4 3,4-dichloro-5-methoxybenzaldehyde 
• 63001-37-6 3,4-dichloro-5-methoxybenzoic acid 
• 63001-36-5 3,4-Dichloro-5-hydroxybenzoic acid 
• 89530-05-2 4,5-dichloro-6-methoxy-2-methyl-2-phenyl-1H-indene-1,3(2H)-dione 
• 89530-04-1 4,5-dichloro-6-methoxy-2-phenyl-1H-indene-1,3(2H)-dione 
• 876291-40-6 3-tert-butoxy-2-{2-[4,5-dichloro-2-(4-fluoro-phenyl)-6-methoxy-1,3-dioxo-indan-2-yl]-ethylamino}-propionic acid tert-butyl ester 
• 876291-48-4 3-tert-butoxy-2-({2-[4,5-dichloro-2-(4-fluoro-phenyl)-6-methoxy-1,3-dioxo-indan-2-yl]-ethyl}-methyl-amino)-propionic acid tert-butyl ester 
• 876291-71-3 ({2-[4,5-dichloro-2-(4-fluoro-phenyl)-6-methoxy-1,3-dioxo-indan-2-yl]-ethyl}-methyl-amino)-phenyl-acetic acid tert-butyl ester 
• 876291-41-7 {2-[4,5-dichloro-2-(4-fluoro-phenyl)-6-methoxy-1,3-dioxo-indan-2-yl]-ethylamino}-phenyl-acetic acid tert-butyl ester 

Relevant academic research and scientific papers

(Acylaryloxy)acetic Acid Diuretics. 5. acetic Acids

Investigation of the chemistry of the potent uricosuric diuretic indacrinone (MK-196) prompted the synthesis of a series of 3-oxo derivatives, i.e., the indan-1,3-diones.In general, both pharmacological parameters (uricosuria and diuresis) were significantly less pronounced with the 1,3-diones than with the parent 1-oxo compounds

(1-Oxo-7,8-disubstituted-1,2,3,4-tetrahydro-6-naphthyloxy)- and (3,4-disubstituted-5-oxo-6,7,8,9-tetrahydro-5H-benzocycloheptene-2-yloxy) acetic acids and derivatives

(1-Oxo-7,8-disubstituted-1,2,3,4-tetrahydro-6-naphthyloxy)- and (3,4-disubstituted-5-oxo-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yloxy)acetic acids, their carboxylate salts, and the amide and 5-tetrazole derivatives thereof are active as diuretic and sal

Pharmaceutical compositions and method of treatment employing 1,3-dioxo-2,2-disubstituted indanyloxy alkanoic acids

[1,3-Dioxo-2-substituted and 2,2-disubstituted-indanyloxy(or thio)]alkanoic acids and their salts, esters and amides are disclosed. The products display a dual pharmaceutical utility in that they exhibit diuretic, saluretic and uricosuric activity. The ac