63190-44-3

Basic information

• Product Name: ethyl cyclopropanecarbimidate, HCl
• Synonyms: ethyl cyclopropanecarbimidate, HCl;CyclopropanecarboxiMidic acid, ethyl ester, hydrochloride;Cyclopropanecarboximidic acid, ethyl ester, hydrochloride (1:1)
• CAS NO: 63190-44-3
• Molecular Formula: C₆H₁₁NO*ClH
• Molecular Weight: 149.62
• Product Categories: Cycloalkanes
• Mol File: 63190-44-3.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl cyclopropanecarbimidate, HCl(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl cyclopropanecarbimidate, HCl(63190-44-3)
• EPA Substance Registry System: ethyl cyclopropanecarbimidate, HCl(63190-44-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 63190-44-3(Hazardous Substances Data)

Usage

General Description

Ethyl cyclopropanecarbimidate hydrochloride is a compound formed from the reaction between ethyl cyclopropanecarbimidate and hydrochloric acid. It is a derivative of the carbamate functional group and is often used as a reagent in organic synthesis and pharmaceutical research. Ethyl cyclopropanecarbimidate hydrochloride has been found to have potential biological activity, particularly as an inhibitor of enzyme activity. It is also used in the preparation of various pharmaceutical compounds and has been studied for its potential as a therapeutic agent in the treatment of certain diseases. ethyl cyclopropanecarbimidate, HCl is typically handled and stored in accordance with standard laboratory safety protocols due to its potential for irritant and toxic effects.

Upstream product

• 64-17-5 ethanol 
• 5500-21-0 cyclopropropanecarbonitrile 
• 60-29-7 diethyl ether 

Downstream Products

• 57297-29-7 cyclopropylcarboxamidine hydrochloride 
• 1159734-92-5 [1-(5-cyclopropyl-4H-[1,2,4]triazol-3-yl)-cyclopropyl]-carbamic acid benzyl ester 
• 3005-30-9 3,5-bis(4-methylphenyl)-1H-1,2,4-triazole 
• 55368-79-1 3,5-bis(4-bromophenyl)-1H-1,2,4-triazole 
• 1038410-94-4 3,5-bis-(4-fluoro-phenyl)-1H-(1,2,4)triazole 
• 2039-06-7 3,5-diphenyl-1,2,4-triazole 
• 100677-40-5 3,5-bis(3-chlorophenyl)-1H-1,2,4-triazole 

Relevant articles and documents

Synthesis and molecular docking study of some 5,6-dichloro-2-cyclopropyl-1H-benzimidazole derivatives bearing triazole, oxadiazole, and imine functionalities as potent inhibitors of urease

A new series of benzimidazole compounds including hydrazinecarbothioamide, 1,2,4-triazole, 1,3,4-oxadiazole and imine function were synthesized starting from 5,6-dichloro-2-cyclopropyl-1H-benzimidazole. All of the benzimidazole derivatives exhibited good urease inhibitor activity. Compound 6a proved to be the most potent showing an enzyme inhibitory activity with an IC50?=?0.06?μM. Molecular docking studies were also conducted on enzyme extracted from Jack bean urease to identify the binding mode of the newly synthesized compounds.

ASK1 inhibitor, derivative, preparation method, pharmaceutical composition and application thereof

The invention discloses an ASK1 inhibitor, a derivative, a preparation method, a pharmaceutical composition and application thereof. The structure of the compound is shown as a formula I. The ASK1 inhibitor derivative relates to an isomer, a diastereoisom

IMIDAZOPIPERAZINONE INHIBITORS OF TRANSCRIPTION ACTIVATING PROTEINS

The present disclosure relates to heterocyclic compounds and methods which may be useful as inhibitors of transcription activating proteins such as CBP and P300 for the treatment or prevention of diseases such as proliferative diseases, inflammatory disorders, autoimmune diseases, and fibrotic diseases.