57308-66-4Relevant articles and documents
An efficient and general approach to β-functionalized ketones
Jingliang, Jiao,Nguyen, Larry X.,Patterson, Dennis R.,Flowers II, Robert A.
, p. 1323 - 1326 (2008/01/01)
Figure presented The oxidation of selected anlons (N3 -, SCN-, I-, and Br-) by eeric ammonium nitrate (CAN) in the presence of substituted cyclopropyl alcohols provides a novel approach to β-functionalized ketones. The protocol has a number of advantages including short reaction times, ease of reagent handling, and mild, neutral reaction conditions. Overall, this method provides an alternative pathway to important starting materials and intermediates in organic synthesis.
FORMATION OF ISOMERIC β-ISOTHIOCYANATO AND β-THIOCYANATO CARBONYL COMPOUNDS IN THE REACTION OF THIOCYANIC ACID WITH α,β-UNSATURATED ALDEHYDES AND KETONES
Peretokin, A. V.,Shutalev, A. D.,Chupin, V. V.,Mergenova, A. M.,Ignatova, L. A.,et al.
, p. 912 - 918 (2007/10/02)
The structure of the products from the reaction of α,β-unsaturated aldehydes and ketones with thiocyanic acid was established by IR and 1H and 13C NMR spectroscopy.It was shown that the addition temperature and the structure of the obtained product depend on the structures of the initial compounds.It was established that the reactions of α,β-unsaturated aldehydes and ketones not containing methyl substituents at the Cβ carbon atom lead to the formation of isomeric β-isothiocyanato and β-thiocyanato carbonyl compounds, whereas the β-isothionato derivatives are formed exclusively in the case of t he β-methyl- and β,β-dimethyl substituted α,β-unsaturated aldehydes and ketones.
