463-56-9

Usage

Uses

Used in Chemical Synthesis:
Thiocyanic acid is used as a reagent in the chemical synthesis of various compounds, such as thiourea, dyes, and pharmaceuticals. Its ability to form thiocyanate salts with metal ions makes it a versatile building block in the chemical industry.
Used in Analytical Chemistry:
Thiocyanic acid is utilized as an analytical reagent for the detection and determination of metal ions, particularly in the analysis of heavy metals like gold, silver, and mercury. Its high affinity for these metals allows for accurate and sensitive measurements.
Used in Agriculture:
In the agricultural industry, thiocyanic acid is employed as a component in the formulation of certain pesticides and herbicides. Its ability to inhibit specific metabolic pathways in pests and weeds contributes to its effectiveness in these applications.
Used in Metallurgy:
Thiocyanic acid is used in the metallurgical industry for the extraction and purification of metals, such as gold and silver. Its ability to form stable complexes with these metals aids in their separation and recovery from ores.
Used in Environmental Applications:
Thiocyanic acid is employed in environmental applications for the treatment of wastewater and the removal of heavy metal contaminants. Its strong chelating properties enable the efficient removal of toxic metals from industrial effluents, thus reducing their environmental impact.

InChI:InChI=1/CHNS/c2-1-3/h3H

Upstream product

• 110-89-4 piperidine 
• 57-06-7 N-allyl isothiocyanate 
• 67-56-1 methanol 
• 75-15-0 carbon disulfide 
• 67764-33-4 cyclopentyl nitrite 
• 506-68-3 bromocyane 
• 960622-40-6 thiooxalic acid-1-oxime 
• 64-17-5 ethanol 
• 408350-33-4 ethyl-cyano-disulfane 
• 118020-16-9 glycoloyl thiocyanate 
• 57-12-5 cyanide^(1-) 
• 860754-37-6 5-nitroso-4-phenyl-2-p-tolylamino-thiazole 
• 333-20-0 potassium thioacyanate 
• 1147550-11-5 ammonium thiocyanate 

Downstream Products

• 556-64-9 methyl thiocyanate 
• 701-57-5 1-methylthio-4-nitro-benzene 
• 63917-28-2 3,4-dihydro-4-phenyl-2(1H)-quinazolinethione 
• 35036-90-9 trityl thiocyanate 
• 141-84-4 2-thioxo-4-thiazolidinone 
• 24697-49-2 diphenyl bismuth ⁽¹⁺⁾; thiocyanate 
• 592-85-8 mercury(II) thiocyanate 
• 5285-87-0 phenyl thiocyanate 
• 557-42-6 zinc(II) thiocyanate 
• 6846-35-1 5-amino-3H-1,2,4-dithiazole-3-thione 
• 108-04-3 cyano-dithiocarbamic acid 
• 74-90-8 hydrogen cyanide 
• 15192-76-4 copper(II) thiocyanate 
• 10403-66-4 2-hydroxy-ethylmercury ⁽¹⁺⁾; iodide 

Relevant academic research and scientific papers

Photolysis of isothiocyanic acid HNCS in low-temperature matrices. Infrared detection of HSCN and HSNC isomers

A combination of matrix isolation technique and Fourier transform infrared spectroscopy has been used to study the low-temperature photochemistry of isothiocyanic acid HNCS. Near UV photolysis with a medium-pressure mercury lamp of the matrix isolated HNCS/DNCS precursor in nitrogen and argon led to the formation of two unobserved, so far, isomers: thiocyanic acid HSCN and isothiofulminic acid HSNC and their deuterated analogs. Both species are formed as primary products presumably via two reaction channels: formation of the [HNCS] and hydrogen migration leading to the HSCN molecule and formation of the [HNCS] followed by rearrangement to HSCN and HSNC species.

The layered coordination polymer Bi(SCN)3·H2O

Yellow crystals of Bi(SCN)3·H2O are obtained by reacting (BiO)2CO3 and HSCN in aqueous solution. X-ray diffraction on a single-crystal revealed a triclinic lattice (space group P1) with a = 843.6(2) pm, b = 920.4 (2) pm, c = 1210.7(2) pm, α = 109.16(3) °, β = 109.06(3) °, γ = 90.22(3) °, V = 832.8(3)·10 pm, and Z = 4. All thiocyanate anions bind with both ends to different cations. The coordination network expands in plane layers parallel (1 1 0). The water molecule coordinates one of the two independent Bi3+ cations. Dehydration sets in at 100 °C, followed by stepwise thermal decomposition to Bi2S3.

Compounds containing a N-heteroaryl moiety linked to fused ring moieties for the inhibition of NAD(P)H oxidases and platelet activation

The invention relates to compounds containing a N-heteroaryl moiety, which is linked via oxygen, sulfur or nitrogen, or via a methylene bridge and oxygen, sulfur or nitrogen to a fused ring moiety, in particular to the 1,2,3-triazolo[4,5-d]pyrimidine-7-yl radical. The invention also relates to a process for the preparation of said compounds and the use thereof in drugs for the treatment of NAD(P)H oxidases-related diseases and disorders and inhibition of platelet activation.

Chalcone Aziridines. III. Reaction of trans-Chalcone Aziridines with Isocyanates, Isothiocyanates and HSCN

The reaction of 2-aryl-3-aroyl-aziridines 1 with phenyl isocyanate or mustard oils leads to N-phenylcarbamoyl derivatives 2a-q and 2-amino-thiazolines 6a, h, n, r, respectively.From 2m and NaI the imidazolin-2-one 3 was obtained.By treatment of 2 with HSCN the regioisomers 2(3)-ureido-3(2)-rhodano-1.3-diaryl-propan-1-ones 4a, h, m, and 5f were formed.

Kinetics and Mechanism of Reaction of Thiourea Nitrite in a Highly Ionic Medium

The title reaction proceeds by a multistep mechanism with two major paths.Production of colloidal sulphur is also noted.A novel mechanistic approach is proposed, based on the kinetic data obtained and some previous work.The reaction is shown to be a second-order process involving an unusual S-nitrosation of thiourea.