57341-12-5

Basic information

• Product Name: 1,4-Naphthalenedione, 2-(phenylthio)-
• CAS NO: 57341-12-5
• Molecular Formula: C16H10O2S
• Molecular Weight: 266.32
• Mol File: 57341-12-5.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 1,4-Naphthalenedione, 2-(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Naphthalenedione, 2-(phenylthio)-(57341-12-5)
• EPA Substance Registry System: 1,4-Naphthalenedione, 2-(phenylthio)-(57341-12-5)

Safety Data

• Hazardous Substances Data: 57341-12-5(Hazardous Substances Data)

Upstream product

• 217638-23-8 2-phenylsulfanyl-naphthalene-1,4-diol 
• 108-98-5 thiophenol 
• 130-15-4 [1,4]naphthoquinone 
• 1696-17-9 N,N-diethylbenzamide 
• 80227-71-0 β-thiophenylacrolein 
• 882-33-7 diphenyldisulfane 
• 1193-82-4 racemic methyl phenyl sulfoxide 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 27098-65-3 3-phenylsulfanyl-propionaldehyde 

Downstream Products

• 138648-11-0 cis-5-hydroxy-6-phenylsulphanyl-6b,9a-dihydrofuro<3,2-b>naphtho<2,1-d>furan-8(9H)-one 
• 119449-66-0 2-(2-Oxo-cyclobutyl)-3-phenylsulfanyl-[1,4]naphthoquinone 
• 122647-40-9 (1S,4aS,9aS)-9a-Phenylsulfanyl-1-trimethylsilanyloxy-1,4,4a,9a-tetrahydro-anthraquinone 
• 1989-42-0 1,3-dimethoxy-9,10-anthraquinone 
• 20733-99-7 1-hydroxy-3-methoxy-9,10-anthraquinone 
• 129155-19-7 2-acetonyl-3-phenylthio-1,4-naphthoquinone 
• 127636-02-6 2-(3'-chlorophenacyl)-3-phenylthio-1,4-naphthoquinone 
• 127635-96-5 2-(4'-chlorophenacyl)-3-phenylthio-1,4-naphthoquinone 
• 127635-98-7 2-(4'-bromophenacyl)-3-phenylthio-1,4-naphthoquinone 
• 127636-01-5 2-(2'-chlorophenacyl)-3-phenylthio-1,4-naphthoquinone 
• 127636-03-7 2-<2-oxo-2-(2-naphthyl)ethyl>-3-phenylthio-1,4-naphthoquinone 
• 127635-99-8 2-(4'-methoxyphenacyl)-3-phenylthio-1,4-naphthoquinone 
• 127636-00-4 2-(4'-nitrophenacyl)-3-phenylthio-1,4-naphthoquinone 
• 119449-67-1 2-(2-oxo-2-phenylethyl)-3-phenylthio-1,4-naphthoquinone 

Relevant articles and documents

Inhibition of Ca2+-activated and voltage-dependent K+ currents by 2-mercaptophenyl-1,4-naphthoquinone in pituitary GH3 cells: contribution to its antiproliferative effect.

Quinones have been shown to possess antineoplastic activity; however, their effects on ionic currents remain unclear. The effects of 2-mercaptophenyl-1,4-naphthoquinone (2-MPNQ), menadione (MD) and 1,4-naphthoquinone (1,4 NQ) on cell proliferation and ion

Synthesis of carbazoloquinone derivatives and their antileukemic activity via modulating cellular reactive oxygen species

Carbazoloquinone alkaloids are of great interest as privileged structures for anticancer drug molecules. The purpose of this study was to investigate the structure-activity relationships of carbazoloquinone derivatives as anticancer agents. A series of ca

NAPHTHAQUINONE METHYLTRANSFERASE INHIBITORS AND USES THEREOF

Provided herein are compounds of (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, and prodrugs thereof. Also provided are pharmaceutical compositions and methods involving the inventive compounds for the treatment of proliferative diseases (e.g., cancer (e.g., leukemia, breast cancer, melanoma, metastatic cancer) and diseases associated with inappropriate SET8 activity. Also provided are methods for inhibiting SET8 and methods for labelling SET8.