27098-65-3Relevant academic research and scientific papers
Directed addition of sulfur-stabilised carbanions to 1,2,3-trisubstituted aziridines
Craig, Donald,Lu, Pengfei,Mathie, Tanya,Tholen, Niels T.H.
, p. 6376 - 6382 (2010)
Thioether and sulfone-stabilised carbanions possessing varying functional groups enter into highly regioselective, stereospecific ring-opening reactions with vinyl- and hydroxymethyl-substituted aziridines. Some derivatisation reactions of the adducts are
Isolation and asymmetric total synthesis of fungal secondary metabolite hygrophorone B12
Bette, Eileen,Otto, Alexander,Dr?ger, Tobias,Merzweiler, Kurt,Arnold, Norbert,Wessjohann, Ludger,Westermann, Bernhard
, p. 2357 - 2365 (2015)
Hygrophorone B12, a new antifungal constituent from the fruiting bodies of Hygrophorus abieticola, has been isolated and subsquently synthesized in enantiomerically pure form. The total synthesis includes a Sharpless asymmetric dihydroxylation
Enantioselective Synthesis of (?)-Halenaquinone
Goswami, Subir,Harada, Kenichi,El-Mansy, Mohamed F.,Lingampally, Rajinikanth,Carter, Rich G.
supporting information, p. 9117 - 9121 (2018/07/24)
The efficient, 12–14 step (LLS) total synthesis of (?)-halenaquinone has been achieved. Key steps in the synthetic sequence include: (a) proline sulfonamide-catalyzed, Yamada–Otani reaction to establish the C6 all-carbon quaternary stereocenter, (b) multi
Pummerer Cyclization Revisited: Unraveling of Acyl Oxonium Ion and Vinyl Sulfide Pathways
Li, Xin,Carter, Rich G.
supporting information, p. 5541 - 5545 (2018/09/25)
Two viable pathways (vinyl sulfide and acyl oxonium ion) for the Pummerer cyclization have been unraveled that expand the reaction scope and capabilities. Use of Br?nsted-enhanced Lewis acidity was key to realization of the vinyl sulfide pathway, whereas selective complexation of the sulfur lone pair facilitated the unprecedented acyl oxonium ion pathway. Preliminary mechanistic investigations support these hypotheses. A range of substrates have been explored to understand the reaction parameters.
HERBICIDE COMPOSITION
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Paragraph 0481-0484, (2015/11/03)
There is provided a herbicidal composition containing a cyclohexanone compound represented by Formula (I) and at least one compound selected from Group A. Group A: consisting of benoxacor, cloquintocet-mexyl, cyometrinil, dichlormid, fenchlorazole-ethyl,
Structural insights into bioactive thiazolidin-4-one: Experimental and theoretical data
De Oliveira Cardoso, Marcos Veríssimo,Hernandes, Marcelo Zaldini,Moreira, Diogo Rodrigo Magalh?es,De Santana Pontes, Frederico José,De Simoned, Carlos Alberto,Leite, Ana Cristina Lima
, p. 262 - 270 (2015/06/22)
Although viewed as promising drug candidates, few efforts have been addressed towards the structural chemistry of 2-hydrazonothiazolidin-4-ones. Therefore, 2-[(3-phenylsulfanylpropylidene)-hydrazono]thiazolidin-4-one (ATZ3) was synthesized and its crystal and molecular structure was studied by NMR and X-ray single crystal diffraction. The 1H NMR spectral data indicated that the hydrazone group assumes the Econfiguration, which was further confirmed by bi-dimensional NMR and crystallographic data. Despite agreement between most bond lengths and angleswith their expected values, the crystalline packing provided important information with regard to the double bond position involving the C-4 carbon. Quantum chemical calculations at Semiempirical, Density Functional Theory (DFT) and Ab Initio levels provided a good agreement between calculated and structural results provided by X-ray analysis. The system's dimerization energies were also estimated. Statistical and Hierarchic Cluster Analysis (HCA) revealed interesting aspects of the calculations and pointed to the B3LYP as the most accurate in the determination of structure among the methods considered, in spite of some good results achieved by semiempirical schemes.
CYCLOHEXANONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME
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Paragraph 0426-0429, (2014/08/19)
The present invention provides a compound having an excellent efficacy for controlling weeds. A cyclohexanone compound of the formula (I): wherein m is an integer of 1, 2 or 3; n is an integer of any one of 1 to 5; X represents CH2, O, S, S(O)
The synthesis of phosphonic acids derived from homocysteine via transesterification reactions
Picha, Jan,Budesinsky, Milos,Fiedler, Pavel,Jiracek, Jiri
experimental part, p. 80 - 99 (2012/03/09)
An efficient methodology for the synthesis of S-substituted derivatives of phosphonohomocysteine has been developed. It starts from the corresponding thiols and is based on a synthetic sequence consisting of (i) the Kabachnik-Fields reaction, (ii) the tra
Supported cobalt complex-catalysed conjugate addition of indoles, amines and thiols to α,β-unsaturated compounds
Rajabi, Fatemeh,Razavi, Sepideh,Luque, Rafael
experimental part, p. 786 - 789 (2010/09/05)
A highly active and reusable supported Co(ii) complex on SBA-15 shows an excellent activity and selectivity to target products in aza- and thia-Michael conjugate additions of indoles, amines and thiols to α,β-unsaturated compounds under solventless mild reaction conditions. The Co-catalyst was also highly reusable and comparably more active than related catalysts in the reaction.
Synthesis of an enantiopure isoxazolidine monomer for β3-aspartic acid in chemoselective β-oligopeptide synthesis
Ishida, Hiroshi,Carrillo, Nancy,Bode, Jeffrey W.
scheme or table, p. 3258 - 3260 (2009/09/05)
The synthesis of an enantiopure isoxazolidine monomer for the incorporation of β3-aspartic acid residues into β3-oligopeptides via chemoselective α-ketoacid-hydroxylamine amide formation is disclosed. This route involves nitrone cycl
