5737-85-9

Basic information

• Product Name: 4-(3-Nitrophenyl)benzoic acid
• Synonyms: 4-(3-Nitrophenyl)benzoic acid;3'-Nitro-4-biphenylcarboxylic acid
• CAS NO: 5737-85-9
• Molecular Formula: C₁₃H₉NO₄
• Molecular Weight: 243.22
• Mol File: 5737-85-9.mol
• Article Data: 8

Chemical Properties

• Melting Point: >300°
• Boiling Point: 449.1±38.0 °C(Predicted)
• Appearance: /
• Density: 1.358±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 4.00±0.10(Predicted)
• CAS DataBase Reference: 4-(3-Nitrophenyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-Nitrophenyl)benzoic acid(5737-85-9)
• EPA Substance Registry System: 4-(3-Nitrophenyl)benzoic acid(5737-85-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 5737-85-9(Hazardous Substances Data)

Usage

General Description

4-(3-Nitrophenyl)benzoic acid is a chemical compound with the molecular formula C13H9NO4. It is a derivative of benzoic acid and contains a nitro group and a phenyl group. 4-(3-Nitrophenyl)benzoic acid is commonly used in the synthesis of pharmaceuticals and organic compounds. It is also used as a reagent in organic chemistry reactions, particularly in the formation of esters and amides. Additionally, 4-(3-Nitrophenyl)benzoic acid has applications in the dye industry for synthesizing various types of dyes. It is important to handle this chemical with care as it is toxic and can cause skin and eye irritation upon contact.

Upstream product

• 586-76-5 4-Bromobenzoic acid 
• 13331-27-6 m-nitrobenzene boronic acid 
• 74-11-3 para-chlorobenzoic acid 
• 585-79-5 m-nitrobromobenzene 
• 180516-87-4 4-carboxyphenylboronic acid pinacol ester 
• 16278-29-8 3-nitrobenzenediazonium 
• 93-58-3 benzoic acid methyl ester 
• 98-95-3 nitrobenzene 
• 121-90-4 m-nitrobenzoic acid chloride 
• 2113-58-8 3-nitro-1,1'-biphenyl 
• 904-58-5 bis-(3-nitro-benzoyl)-peroxide 
• 65-85-0 benzoic acid 
• 2453-41-0 3-nitroperbenzoic acid 
• 89900-93-6 3'-nitro-[1,1'-biphenyl]-4-carboxylic acid methyl ester 

Downstream Products

• 108620-55-9 ethyl 3'-amino-[1,1'-biphenyl]-4-carboxylate 
• 1021306-28-4 8-[(3'-nitro-biphenyl-4-carbonyl)amino]naphthalene-1,3,5-trisulfonic acid 
• 89900-93-6 3'-nitro-[1,1'-biphenyl]-4-carboxylic acid methyl ester 

Relevant articles and documents

Poly(: O -aminothiophenol)-stabilized Pd nanoparticles as efficient heterogenous catalysts for Suzuki cross-coupling reactions

Poly(o-aminothiophenol) (PATP)-stabilized Pd nanoparticles with Pd nanoparticles embedded in a polymer matrix have been obtained through a facile one-step route by mixing o-aminothiophenol monomer and Pd(NO3)2 in an acidic aqueous solution without additional template or surfactant. The redox reaction between o-aminothiophenol and Pd(NO3)2 leads to the simultaneous formation of a PATP polymer and Pd nanoparticles. The PATP-stabilized Pd nanoparticles have been characterized by TEM, FTIR, XRD, ICP-MS and XPS. Catalytic results showed that PATP-stabilized Pd nanoparticles were highly stable and active catalysts for Suzuki cross-coupling reactions, where high yields could be achieved with arylboronic acid and aryl halides bearing a variety of substituents.

SPECIFIC ANTAGONIST FOR BOTH E- AND P-SELECTINS

Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise a particular glycomimetic linked to a particular BASA (Benzyl Amino Sulfonic Acid).

Pd(DIPHOS)2-catalyzed cross-coupling reactions of organoborons with free or polymer-bound aryl halides.

Bis[1,2-bis(diphenylphosphino)ethane]palladium(0) [Pd(DIPHOS)2] catalyzes cross-coupling reactions of free or polymer-bound aryl halides with organoboron compounds to produce biaryls in overall yields of 60-96%.