573701-88-9

Usage

Uses

Used in Pharmaceutical Industry:
Methyl 2-amino-2-(2-fluorophenyl)acetate is utilized as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs and therapeutic compounds.
Used in Academic Research:
In academic research, methyl 2-amino-2-(2-fluorophenyl)acetate serves as a valuable building block for the production of biologically active molecules. Its potential applications in drug discovery make it a significant tool for scientists working on the development of novel treatments and therapies.
Used in Organic Chemistry:
As a reagent in organic chemistry, methyl 2-amino-2-(2-fluorophenyl)acetate contributes to a wide range of chemical reactions and processes. Its versatility in organic synthesis highlights its importance in the field of chemistry.

Upstream product

• 67-56-1 methanol 
• 84145-28-8 (+/-)-2-amino-2'-fluorophenylacetic acid 
• 446-52-6 2-Fluorobenzaldehyde 
• 137684-19-6 o-fluorophenylglyoxal 
• 132115-73-2 methyl 2-fluoro-α-oxo-benzeneacetate 
• 445-27-2 2'-Fluoroacetophenone 

Downstream Products

• 92268-69-4 (Ethoxycarbonyl)-4 o-fluorophenyl-2 butanoate de methyle 
• 1227294-06-5 (2S,3S,3aS,9bS)-3-ethyl-2-methyl-2-(2-fluorophenyl)-1,2,3,3a,4,9b-hexahydrochromeno[4,3-b]pyrrole-2,3-dicarboxylate 

Relevant academic research and scientific papers

Synthesis of Unprotected 2-Arylglycines by Transamination of Arylglyoxylic Acids with 2-(2-Chlorophenyl)glycine

The transamination of α-keto acids with 2-phenylglycine is an effective methodology for directly synthesizing unprotected α-amino acids. However, the synthesis of 2-arylglycines by transamination is problematic because the corresponding products, 2-arylglycines, transaminate the starting arylglyoxylic acids. Herein, we demonstrate the use of commercially available l-2-(2-chlorophenyl)glycine as the nitrogen source in the transamination of arylglyoxylic acids, producing the corresponding 2-arylglycines without interference from the undesired self-transamination process.

2,3,4,5-TETRAHYDROPYRIDIN-6-AMINE AND 3,4-DIHYDRO-2H-PYRROL-5-AMINE COMPOUND INHIBITORS OF BETA-SECRETASE

The present invention relates to 2,3,4,5-tetrahydropyridin-6-amine and 3,4- dihydro-2H-pyrrol-5-amine compound inhibitors of beta-secretase having the structure shown in Formula (I), wherein the radicals are as defined in the specification. The invention

Rh-catalyzed asymmetric hydrogenation of racemic aldimines via dynamic kinetic resolution

Catalyzed by a rhodium complex of P-stereogenic diphosphine ligand trichickenfootphos (TCFP), asymmetric hydrogenation of racemic aldimines via dynamic kinetic resolution has been realized for the preparation of chiral arylglycines with good yields and enantioselectivities.

Solid phase β-lactams synthesis using the Staudinger reaction, monitored by 19F NMR spectroscopy

We report the use of 19F NMR as a simple means to monitor reactions on a solid phase. Multi-step sequences including protection, coupling, deprotection, condensation, cycloaddition and cleavage steps are described in the case of multicomponent reactions involving fluorinated α-aminoesters, aldehydes and acid chlorides.