34560-28-6

Basic information

• Product Name: Benzonitrile, 2-ethenyl-
• CAS NO: 34560-28-6
• Molecular Formula: C9H7N
• Molecular Weight: 129.161
• Mol File: 34560-28-6.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 2-ethenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 2-ethenyl-(34560-28-6)
• EPA Substance Registry System: Benzonitrile, 2-ethenyl-(34560-28-6)

Safety Data

• Hazardous Substances Data: 34560-28-6(Hazardous Substances Data)

Upstream product

• 34136-59-9 o-ethylbenzonitrile 
• 873-32-5 2-Chlorobenzonitrile 
• 7486-35-3 tri-n-butyl(vinyl)tin 
• 74-85-1 ethene 
• 57381-41-6 2,5-dibromophenyl cyanide 
• 2042-37-7 o-cyanobromobenzene 
• 4363-34-2 vinylboronic acid 
• 28272-96-0 2-vinylbenzaldehyde 
• 4387-36-4 2-iodobenzonitrile 
• 1066-54-2 trimethylsilylacetylene 
• 1826-67-1 vinyl magnesium bromide 
• 2039-88-5 2-bromostyrene 
• 6630-33-7 ortho-bromobenzaldehyde 
• 544-92-3 copper(I) cyanide 

Downstream Products

• 145105-01-7 2-[1-(phenylmethyl)-3-pyrrolidinyl]benzonitrile 
• 93-56-1 phenylethane 1,2-diol 
• 1373919-59-5 (R)-3-(hydroxymethyl)isobenzofuran-1(3H)-one 
• 27916-43-4 3-(2-cyanophenyl)propionic acid 
• 2234-26-6 bicyclo[2.2.1]heptane-2-carbonitrile 

Relevant articles and documents

Olefination via Cu-Mediated Dehydroacylation of Unstrained Ketones

The dehydroacylation of ketones to olefins is realized under mild conditions, which exhibits a unique reaction pathway involving aromatization-driven C-C cleavage to remove the acyl moiety, followed by Cu-mediated oxidative elimination to form an alkene between the α and β carbons. The newly adopted N′-methylpicolinohydrazonamide (MPHA) reagent is key to enable efficient cleavage of ketone C-C bonds at room temperature. Diverse alkyl- and aryl-substituted olefins, dienes, and special alkenes are generated with broad functional group tolerance. Strategic applications of this method are also demonstrated.

Rhenium-Catalyzed Decarboxylative Tri-/Difluoromethylation of Styrenes with Fluorinated Carboxylic Acid-Derived Hypervalent Iodine Reagents

Herein, unprecedented rhenium-catalyzed decarboxylative oxytri-/difluoromethylation and Heck-type trifluoromethylation of styrenes have been developed by using hypervalent iodine(III) reagents derived from cheap, stable, and easy-handling fluorinated carboxylic acids. Mechanistic studies revealed a radical decarboxylative trifluoromethylation pathway occurring in these reactions.

Unlocking Mizoroki–Heck-Type Reactions of Aryl Cyanides Using Transfer Hydrocyanation as a Turnover-Enabling Step

A new transfer hydrofunctionalization strategy to turnover H-MII-X complexes has enabled both intra- and intermolecular Mizoroki–Heck (MH)-type reactions of aryl cyanides that are challenging to realize under traditional, basic conditions. Initially, a cascade carbonickelation/MH reaction of 2-cyanostyrenes was achieved using a key alkyne transfer hydrocyanation step. Mechanistic experiments supported the proposed catalytic cycle, including the turnover-enabling transfer hydrocyanation step. The reactivity was then extended to the intermolecular MH reaction of benzonitriles and styrenes.