5338-96-5

Basic information

• Product Name: 3-Cyanostyrene
• Synonyms: 3-ethenylbenzonitrile; 4-{(2E)-2-[1-(3,4-dichlorophenyl)ethylidene]hydrazino}-5,6-dimethyl-2-phenylpyrimidine
• CAS NO: 5338-96-5
• Molecular Formula: C₉H₇N
• Molecular Weight: 385.2897
• Mol File: 5338-96-5.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 449.7°C at 760 mmHg
• Flash Point: 225.8°C
• Density: 1.26g/cm³
• Vapor Pressure: 2.81E-08mmHg at 25°C
• Refractive Index: 1.628
• CAS DataBase Reference: 3-Cyanostyrene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyanostyrene(5338-96-5)
• EPA Substance Registry System: 3-Cyanostyrene(5338-96-5)

Safety Data

• Hazardous Substances Data: 5338-96-5(Hazardous Substances Data)

Upstream product

• 74-85-1 ethene 
• 6952-59-6 3-cyanobromobenzene 
• 2039-86-3 3-bromostyrene 
• 86164-70-7 2-methyl-2-phenylmalononitrile 
• 108-05-4 vinyl acetate 
• 24964-64-5 3-Cyanobenzaldehyde 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 69113-59-3 3-iodobenzonitrile 
• 1066-54-2 trimethylsilylacetylene 
• 2065-66-9 methyl-triphenylphosphonium iodide 
• 7486-35-3 tri-n-butyl(vinyl)tin 
• 57381-41-6 2,5-dibromophenyl cyanide 
• 15411-43-5 3-vinylaniline 

Downstream Products

• 28447-20-3 3-vinylbenzoic acid 
• 145105-02-8 3-[1-(Phenylmethyl)-3-pyrrolidinyl]benzonitrile 
• 193290-27-6 3-(2-hydroxyethyl)benzonitrile 
• 352616-04-7 cis-2-(3-cyanophenyl)-cyclopropane-1-carboxylic acid 
• 62584-68-3 3-(3-(4-chlorophenyl)-3-oxopropyl)benzonitrile 

Relevant articles and documents

Copper-Catalyzed Radical 1,2-Carbotrifluoromethylselenolation of Alkenes under Ambient Conditions

We have described a copper-catalyzed radical 1,2-carbotrifluoromethylselenolation of alkenes using the readily available alkyl halides and (Me4N)SeCF3 salt. Critical to the success is the use of a proline-based N,N,P-ligand to enhance the reducing capabil

Mur ligases inhibitors with azastilbene scaffold: Expanding the structure–activity relationship

Antibiotic resistance represents one of the biggest public health challenges in the last few years. Mur ligases (MurC–MurF) are involved in the synthesis of UDP-N-acetylmuramyl-pentapeptide, the main building block of bacterial peptidoglycan polymer. They are essential for the survival of bacteria and therefore important antibacterial targets. We report herein the synthesis and structure–activity relationships of Mur ligases inhibitors with an azastilbene scaffold. Several compounds showed promising inhibitory potencies against multiple ligases and one compound also possessed moderate antibacterial activity. These results represent a solid ground for further development and optimization of structurally novel antimicrobial agents to combat the rising bacterial resistance.

A convenient reagent for the conversion of aldoximes into nitriles and isonitriles

For the dehydroxylation of aldoximes with 4-nitro-1-((trifluoromethyl)sulfonyl)-imidazole (NTSI), slight modifications of reaction conditions resulted in significantly different reaction paths to provide either nitriles or isonitriles. The challenging conversion of aldoximes into isonitriles was achieved under mild conditions.