57405-08-0 Usage
Uses
Used in Research and Development:
Trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene Dibenzoate is used as a research compound for studying the metabolic pathways of carcinogenic substances, particularly Benzopyrene. Its application in this field aids in understanding the mechanisms of carcinogenesis and the potential health risks associated with exposure to such substances.
Used in Environmental and Occupational Health:
trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene Dibenzoate is also used as a biomarker in environmental and occupational health studies. By measuring the levels of trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene Dibenzoate in biological samples, researchers can assess the extent of exposure to Benzopyrene and other related carcinogens in various environments and occupations.
Used in Drug Development:
In the pharmaceutical industry, trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene Dibenzoate may be used as a reference compound in the development of drugs or therapies targeting the metabolic pathways of carcinogens. Understanding the interactions between this metabolite and potential therapeutic agents can help in the design of more effective treatments for cancer and other related diseases.
Used in Analytical Chemistry:
Trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene Dibenzoate is used as a reference material in analytical chemistry for the development and validation of methods for the detection and quantification of carcinogenic substances and their metabolites in various samples, such as air, water, soil, and biological tissues. This helps in the accurate assessment of environmental contamination and human exposure to these harmful compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 57405-08-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,4,0 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 57405-08:
(7*5)+(6*7)+(5*4)+(4*0)+(3*5)+(2*0)+(1*8)=120
120 % 10 = 0
So 57405-08-0 is a valid CAS Registry Number.
57405-08-0Relevant academic research and scientific papers
Preparation of Enantiomers of (+/-)-trans-7β,8α-Dihydroxy-9α,10α-epoxy-7,8,9,10-tetrahydrobenzopyrene
Iyer, Radhakrishnan P.,Slaga, Thomas J.,Pal, Bimal C.
, p. 275 - 278 (2007/10/02)
(+/-)-trans-7,8-Dihydroxy-7,8-dihydrobenzopyrene (VII), obtained from 7,8,9,10-tetrahydrobenzopyrene-7(8H)-one (I) by modifications and improvements of the reported procedures, has been converted into its di-(-) and (+)-menthoxyacetate derivatives in 82percent yield.The diastereomers have been separated by liquid chromatography on Lichrosorp Si 60 (30μ) column (100 cm x 1 cm dia.) using methylene chloride-ethyl acetate (99.4/0.6, v/v) as eluant.The enantiomers are liberated from the separated diastereomers by methanolysis with catalytic amount of sodium methoxide and converted into the enantiomers of (+/-)-trans-7β,8α-dihydroxy- 9α,10α-epoxy-7,8,9,10-tetrahydrobenzopyrene by m-chloroperbenzoic acid in an overall yield of 30percent.The CD and the UV spectra of the diastereomers and the enantiomers are reported.
