57413-29-3Relevant academic research and scientific papers
NFSI-catalyzed S[sbnd]S bond exchange reaction for the synthesis of unsymmetrical disulfides
Hu, Qingyue,Li, Zheng-Yi,Song, Mengjie,Sun, Xiaoqiang,Yang, Ke
supporting information, (2022/01/26)
The metal-free S[sbnd]S bond exchange reaction of symmetrical disulfides catalyzed by NFSI is described. This novel protocol provides a facile and efficient approach to accessing important unsymmetrical disulfides. Furthermore, this strategy could also be utilized in the late-stage functionalization of amino acids, drugs, and natural products. The broad substrate scope, good functional group tolerance and easy accessibility of catalyst indicate that this strategy affords a green and practical complementary method to various unsymmetrical disulfides.
Sodium Tellurite as a Mild and Selective Oxidizing Agent for Thiols: Its Use in the One-Pot Synthesis of Unsymmetrical Disulfides
Suzuki, Hitomi,Kawato, Sei-ichi,Nasu, Akira
, p. 626 - 627 (2007/10/02)
Sodium tellurite acts as a mild and highly selective oxidizing agent for thiols under phase-transfer conditions at room temperature.Aromatic and benzylic thiols are rapidly converted to disulfides.Short-chain primary thiols undergo oxidation in preference to long-chain thiols.Secondary thiols are sluggish in oxidation and tertiary thiols remain intact.No overoxidation of the sulfur atom is observed.Similar results are also obtained with sodium tellurate.
Desulfurization of Organic Trisulfides by Tris(dialkylamino)phosphines. Mechanistic Aspects
Harpp, David N.,Ash, David K.,Smith, Roger A.
, p. 5155 - 5160 (2007/10/02)
Tris(dialkylamino)phosphines effect a rapid desulfurization of trisulfides to disulfides under mild conditions.The reaction mechanism involves a bimolecular process, proceeding by the rate-determining formation of a phosphonium salt intermediate.The central sulfur atom of a diaryl trisulfide is removed in the process, while a dialkyl trisulfide loses a terminal sulfur atom to the aminophosphine.
