57433-93-9

Basic information

• Product Name: Phenol, 4-(methoxymethoxy)-
• CAS NO: 57433-93-9
• Molecular Formula: C8H10O3
• Molecular Weight: 154.166
• Mol File: 57433-93-9.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Phenol, 4-(methoxymethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-(methoxymethoxy)-(57433-93-9)
• EPA Substance Registry System: Phenol, 4-(methoxymethoxy)-(57433-93-9)

Safety Data

• Hazardous Substances Data: 57433-93-9(Hazardous Substances Data)

Upstream product

• 130252-97-0 4-(methoxymethoxy)phenyl 2-tetrahydropyranyl ether 
• 107-30-2 chloromethyl methyl ether 
• 123-31-9 hydroquinone 
• 1335101-41-1 (3E,5E)-(1Ss)-(p-tolylsulfinyl)hepta-3,5-dien-2-one 
• 109-87-5 Dimethoxymethane 
• 4497-29-4 bis(bromomethyl) ether 

Downstream Products

• 916265-20-8 4,4'-bis[4-(methoxymethoxy)phenoxy]diphenyl ether 
• 5024-81-7 4,4'-(bis(p-hydroxyphenoxy))diphenyl ether 
• 476003-33-5 2-(2-propenyl)-4-(methoxymethoxy)phenol 
• 476003-34-6 1-(tert-butyldimethylsilyloxy)-2-(2-propenyl)-4-(methoxymethoxy)benzene 
• 476003-42-6 (E)-3-[(2S,3S)-3-(2-Hydroxy-5-methoxymethoxy-benzyl)-2-methyl-oxiranyl]-acrylic acid methyl ester 
• 476003-54-0 3-[2-(tert-butyldimethylsilyloxy)-5-(methoxymethoxy)phenyl]propane-1,2-diol 
• 476003-36-8 (E)-4-[2-(tert-butyldimethylsilyloxy)-5-(methoxymethoxy)phenyl]-2-methyl-2-buten-1-ol 
• 476003-37-9 (2S,3S)-4-[2-(tert-butyldimethylsilyloxy)-5-(methoxymethoxy)phenyl]-2-methyl-2,3-epoxy-butan-1-ol 
• 476003-55-1 (2R,3R)-4-[2-(tert-butyldimethylsilyloxy)-5-(methoxymethoxy)phenyl]-2-methyl-2,3-epoxy-butan-1-ol 
• 476003-35-7 methyl (E)-4-[2-(tert-butyldimethylsilyloxy)-5-(methoxymethoxy)phenyl]-2-methyl-2-butenoate 
• 476003-41-5 methyl (2E,4S,5S)-6-[2-(tert-butyldimethylsilyloxy)-5-(methoxymethoxy)phenyl]-4-methyl-4,5-epoxy-2-hexenoate 
• 476003-56-2 methyl (2E,4R,5R)-6-[2-(tert-butyldimethylsilyloxy)-5-(methoxymethoxy)phenyl]-4-methyl-4,5-epoxy-2-hexenoate 
• 476003-49-3 4-benzenesulfonyl-1-(6-methoxymethoxy-2-methyl-2H-chromen-2-yl)-4,8-dimethyl-non-7-en-3-ol 
• 476003-50-6 acetic acid 2-benzenesulfonyl-1-[2-(6-methoxymethoxy-2-methyl-2H-chromen-2-yl)-ethyl]-2,6-dimethyl-hept-5-enyl ester 

Relevant articles and documents

6,7-DIHYDRO-5H-PYRIDO[2,3-C]PYRIDAZINE DERIVATIVES AND RELATED COMPOUNDS AS BCL-XL PROTEIN INHIBITORS AND PRO-APOPTOTIC AGENTS FOR TREATING CANCER

The present invention discloses 6,7-dihydro-5H-pyrido[2,3- c]pyridazine, 1,2,3,4-tetrahydroquinoline, 1H-indole, 3,4- dihydro-2H-1,4-benzoxazine, 1H-pyrrolo[2,3-b]pyridin-1-yl, 7H- pyrrolo[2,3-c]pyridazine, 5H,6H,7H,8H,9H-pyridazino[3,4-b]azepine derivatives and related compounds of formula (I) as Bcl-xL protein inhibitors for use as pro-apoptotic agents for treating cancer, autoimmune diseases or immune system diseases. Formula (I). The description discloses the preparation of exemplary compounds (e.g. pages 113 to 354 examples 1 to 221) as well as pharmacological studies with relevant data (e.g. pages 355 to 367; examples A to E; tables 1 to 5). Exemplary compounds are e.g. 2-{6-[(1,3-benzothiazol-2-yl) amino]-1,2,3,4-tetrahydroquinolin-1-yl}-1,3-thiazole-4-carboxylic acid (example 1) or e.g. 3-{1-[(adamantan-1-yl)methyl]-5- methyl-1H-pyrazol-4-yl}-6-{3-[(1,3-benzothiazol-2-yl)amino]-4- methyl-5H,6H,7H,8H-pyrido[2,3-c]pyridazin-8-yl]pyridine-2-carboxylic acid (example 24).

Anchimerically Assisted Selective Cleavage of Acid-Labile Aryl Alkyl Ethers by Aluminum Triiodide and N, N-Dimethylformamide Dimethyl Acetal

Aluminum triiodide is harnessed by N,N-dimethylformamide dimethyl acetal (DMF-DMA) for the selective cleavage of ethers via neighboring group participation. Various acid-labile functional groups, including carboxylate, allyl, tert-butyldimethylsilyl (TBS), and tert-butoxycarbonyl (Boc), suffer the conditions intact. The method offers an efficient approach to cleaving catechol monoalkyl ethers and to uncovering phenols from acetal-type protecting groups such as methoxymethyl (MOM), methoxyethoxymethyl (MEM), and tetrahydropyranyl (THP) chemoselectively.

Gem difluorocompounds as depigmenting or lightening agents

The present invention relates to a compound having the formula (I), as well as a method for preparing such a compound, a cosmetic or pharmaceutic composition containing such a compound, and the use thereof as a depigmenting, lightening, bleaching or whitening agent and for treating pigmentation disorders, notably by topical application on the skin.