4497-29-4

Basic information

• Product Name: Bis(bromomethyl) ether
• Synonyms: Dibrom ether;Dibromomethyl ether;Oxybis(bromomethane)
• CAS NO: 4497-29-4
• Molecular Formula: C₂H₄Br₂O
• Molecular Weight: 203.86
• Mol File: 4497-29-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: -34°C
• Boiling Point: 154.5°C (estimate)
• Appearance: /
• Density: 2.2013
• Refractive Index: 1.5460 (estimate)
• CAS DataBase Reference: Bis(bromomethyl) ether(CAS DataBase Reference)
• NIST Chemistry Reference: Bis(bromomethyl) ether(4497-29-4)
• EPA Substance Registry System: Bis(bromomethyl) ether(4497-29-4)

Safety Data

• Hazardous Substances Data: 4497-29-4(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 7726-95-6 bromine 
• 64-19-7 acetic acid 

Downstream Products

• 109-87-5 Dimethoxymethane 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 544-01-4 isopentyl ether 
• 622-95-7 4-chlorobenzyl bromide 
• 5368-60-5 dimethyl ether α,α'-bis(triphenylphosphonium) bromide 
• 104-81-4 4-Methylbenzyl bromide 
• 628-90-0 bis(methoxymethyl)ether 
• 5783-77-7 phenyl-4-phenyl-4-(1,3-dioxolane)ketone 
• 120-12-7 anthracene 
• 101-81-5 Diphenylmethane 
• 793-23-7 1,4-dibenzylbenzene 
• 15180-20-8 1,3-dibenzylbenzene 
• 74-83-9 methyl bromide 
• 64-18-6 formic acid 

Relevant articles and documents

An expeditious and efficient bromomethylation of thiols: Enabling bromomethyl sulfides as useful building blocks

A facile and highly efficient method for the bromomethylation of thiols, using paraformaldehyde and HBr/AcOH, has been developed, which advantageously minimizes the generation of highly toxic byproducts. The preparation of 22 structurally diverse α-bromomethyl sulfides illustrates the chemo-tolerant applicability while bromo-lithium exchange and functionalization sequences, free radical reductions, and additions of the title compounds demonstrate their synthetic utility.