5744-59-2

Usage

Chemical Properties

White solid

InChI:InChI=1/C6H8N2O2/c1-4-3-5(6(9)10)7-8(4)2/h3H,1-2H3,(H,9,10)

Upstream product

• 60-34-4 methylhydrazine 
• 696-22-0 5-methyl-2H-pyrazole-3-carboxylic acid 
• 77-78-1 dimethyl sulfate 
• 4027-57-0 ethyl 5-methyl-1H-pyrazole-3-carboxylate 
• 615-79-2 ethyl 2,4-diketopentanoate 
• 5744-51-4 ethyl 1,5-dimethyl-1H-pyrazole-3-carboxylate 
• 10250-61-0 1,5-dimethyl-1H-pyrazole-3-carboxylic acid methyl ester 

Downstream Products

• 49783-84-8 1,5-dimethyl-1H-pyrazole-3-carbonyl chloride 
• 1227191-76-5 N-[3-(5-{[(1S)-1-cyclohexyl-2-(methylamino)-2-oxoethyl]carbamoyl}furan-2-yl)benzyl]-1,5-dimethyl-1H-pyrazole-3-carboxamide 
• 1403333-47-0 (S)-N-(1-(3-(3-Chloro-4-cyano-5-fluorophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1,5-dimethyl-1H-pyrazol-3-yl)-1,2,4-oxadiazole-3-carboxamide 
• 1313389-01-3 3-benzyl-8-(1,5-dimethyl-1H-pyrazol-3-yl)-1H-purine-2,6(3H,7H)-dione 
• 1297536-62-9 1,5-dimethyl-1H-pyrazole-3-carboxylic acid {2-[5-(3,4-dichlorophenyl)furan-2-yl]ethyl}amide 

Relevant academic research and scientific papers

PYRAZOLE DERIVATIVES AS H4 ANTAGONIST COMPOUNDS

The disclosures herein relate to novel compounds of formula (1): and salts thereof, wherein A; X;n; R1 and R2 are defined herein, and their use in treating, preventing, ameliorating, controlling or reducing the risk of disorders associated with H4 receptors.

N(pyrazol-3-yl) benzamides and pharmaceutical compositions

The invention relates to a compound useful for treating epilepsy selected from the compounds of the general formula: STR1 in which R1 is C1 -C4 alkyl, R2 is C1 -C4 alkyl, R3 is selected from hydrogen, C1 -C4 alkyl, C1 -C4 alkoxy and C1 -C4 hydroxyalkyl, and R4 is selected from hydrogen, C1 -C4 alkyl, C2 -C7 alkanoyl and C1 -C4 hydroxyalkyl.

3-Isoxazoyl derivatives endowed with anticonvulsant activity, procedure for their preparation and their pharmaceutical compositions

The object of the invention is heterocyclic compounds of general formula (I) endowed with anticonvulsant activity: STR1 in which Y is selected from --O--, --S-- and STR2 R4 being H or optionally substituted alkyl, acyl or benzyl, Z is selected

Pyrazolodiazepines. 1,3 (and 2,3) dialkyl 4,6 dihydro 8 arylpyrazolo[4,3 e][1,4] diazepin 5 ones as antianxiety agents

A series of 1, 3 (and 2, 3) dialkyl 4, 6 dihydro 8 arylpyrazolo [4, 3 e][1, 4] diazepin 5 ones was synthesized and evaluated for psychotropic activity. Intermediates are new dialkylnitropyrazolyl aryl ketones prepared from dialkylnitropyrazolecarboxylic acids. Many of these pyrazolodiazepines exhibit high CNS activity in animals. One compound, 1 ethyl 4, 6 dihydro 3 methyl 8 phenylpyrazolo [4, 3 e] [1, 4] diazepin 5 (1H) one is about as potent as diazepam as an antianxiety agent with less sedative properties and is being studied in the clinic.