57489-93-7

Basic information

• Product Name: 5-PHENYL-FURAN-2-CARBONYL CHLORIDE
• Synonyms: AKOS BB-8289;5-PHENYL-FURAN-2-CARBONYL CHLORIDE;ASISCHEM Z32835
• CAS NO: 57489-93-7
• Molecular Formula: C₁₁H₇ClO₂
• Molecular Weight: 206.63
• Mol File: 57489-93-7.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 329°Cat760mmHg
• Flash Point: 152.8°C
• Appearance: /
• Density: 1.26g/cm³
• Vapor Pressure: 0.000183mmHg at 25°C
• Refractive Index: 1.564
• CAS DataBase Reference: 5-PHENYL-FURAN-2-CARBONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-PHENYL-FURAN-2-CARBONYL CHLORIDE(57489-93-7)
• EPA Substance Registry System: 5-PHENYL-FURAN-2-CARBONYL CHLORIDE(57489-93-7)

Safety Data

• RIDADR: UN3261
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 57489-93-7(Hazardous Substances Data)

Usage

General Description

5-PHENYL-FURAN-2-CARBONYL CHLORIDE is a chemical compound with the molecular formula C11H7ClO2. It is a derivative of furan, a five-membered aromatic heterocycle containing an oxygen atom. 5-PHENYL-FURAN-2-CARBONYL CHLORIDE is a carbonyl chloride, which means it contains a carbonyl group (C=O) attached to a chlorine atom. It is commonly used in organic synthesis as a reagent for introducing the carbonyl chloride functional group into various organic compounds. The presence of the phenyl group in the molecule also provides unique reactivity and potential applications in the development of pharmaceuticals and agrochemicals. However, it is important to handle this compound with caution as it is a reactive and potentially hazardous chemical.

InChI:InChI=1/C11H7ClO2/c12-11(13)10-7-6-9(14-10)8-4-2-1-3-5-8/h1-7H

Upstream product

• 585-70-6 5-bromo-furan-2-carboxylic acid 
• 52939-03-4 5-phenylfuran-2-carboxylic acid methyl ester 
• 2527-99-3 methyl 5-bromo-2-furoate 
• 98-80-6 phenylboronic acid 
• 52938-97-3 5-phenylfuran-2-carboxylic acid 
• 79-37-8 oxalyl dichloride 
• 62-53-3 aniline 
• 88-14-2 2-furanoic acid 

Downstream Products

• 661462-23-3 (1,4-diaza-bicyclo[3.2.2]non-4-yl)-(5-phenyl-furan-2-yl)-methanone 
• 22078-90-6 2-hydroxymethyl-5-phenylfuran 

Relevant articles and documents

Discovery of a series of 5-phenyl-2-furan derivatives containing 1,3-thiazole moiety as potent Escherichia coli β-glucuronidase inhibitors

Gut microbial β-glucuronidases have drawn much attention due to their role as a potential therapeutic target to alleviate some drugs or their metabolites-induced gastrointestinal toxicity. In this study, fifteen 5-phenyl-2-furan derivatives containing 1,3

Thiazolidin-2-cyanamides derivatives as novel potent Escherichia coli β-glucuronidase inhibitors and their structure–inhibitory activity relationships

Gut microbial β-glucuronidases have the ability to deconjugate glucuronides of some drugs, thus have been considered as an important drug target to alleviate the drug metabolites-induced gastrointestinal toxicity. In this study, thiazolidin-2-cyanamide de

Synthesis and SAR of 5-aryl-furan-2-carboxamide derivatives as potent urotensin-II receptor antagonists

The synthesis and biological evaluation as potential urotensin-II receptor antagonists of a series of 5-arylfuran-2-carboxamide derivatives 1, bearing a 4-(3-chloro-4-(piperidin-4-yloxy)benzyl)piperazin-1-yl group, are described. The results of a systemat