57500-51-3Relevant articles and documents
Synthesis method of 4-chlorothiophene-2-carbonyl derivative
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Paragraph 0038-0040, (2019/03/08)
The invention discloses a synthesis method of a 4-chlorothiophene-2-carbonyl derivative. A thiophene-2-carbonyl derivative is used as a raw material and reacts with symclosene and aluminum trichloride, and liquid separation and concentration are performed to obtain the 4-chlorothiophene-2-carbonyl derivative. The synthesis method adopts one-step reaction, the yield is not lower than 80%, the production process is decreased while the yield is improved, and the cost is reduced; the used raw materials and reagents are easy to obtain, reaction conditions are mild, post-treatment and purification is easy to operate, and large-scale production can be achieved.
A convenient synthesis of new halothienyl β-aminoacids as versatile building blocks
Renault, Olivier,Dallemagne, Patrick,Rault, Sylvain
, p. 488 - 494 (2007/10/03)
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