57531-87-0

Usage

Uses

Used in Agricultural Applications:
2,4,5-Trichloro-6-methoxyisophthalonitrile is used as an insect growth regulator for controlling a variety of pests that infest crops and stored products. Its application reason is its effectiveness in disrupting the development of insect larvae by inhibiting the formation of the exoskeleton, leading to their eventual death.
Used in Pest Control:
In the pest control industry, 2,4,5-Trichloro-6-methoxyisophthalonitrile is used as a pesticide for its targeted impact on insects, ensuring minimal harm to non-target organisms. This selective action makes it a preferred choice for environmentally conscious pest management practices.

InChI:InChI=1/C9H3Cl3N2O/c1-15-9-5(3-14)6(10)4(2-13)7(11)8(9)12/h1H3

Upstream product

• 67-56-1 methanol 
• 1897-45-6 chlorothalonil 

Relevant academic research and scientific papers

Synthesis and antiinflammatory evaluation of substituted isophthalonitriles, trimesonitriles, benzonitriles, and terephthalonitriles

In an effort to develop nonacidic, nonsteroidal, antiinflammatory agents without gastrointestinal complications, a series of cyanobenzenes was synthesized for antiinflammatory evaluation. Twenty-seven substituted isophthalonitriles, 19 trimesonitriles, 30 benzonitriles, and 16 terephthalonitriles were tested in the rat utilizing the carrageenan-induced pedal edema assay. Based on the performance of phenylbutazone in this assay (43.8% reduction at 100 mg/kg), six compounds, dosed at 50 mg/kg, produced reductions in inflammation comparable to this standard. However, the LD50 value of each compound dosed at this level was in the range of 40-56 mg/kg in the mouse; therefore, further study was not warranted. Fifteen compounds possessed activity in excess of 20% reduction at 200 mg/kg and also possessed LD50 values greater than 300 mg/kg. Of these cyanobenzenes, trimesonitrile, 4-chlorobenzonitrile, 2-chloroterephthalonitrile, and 2-fluoroterephthalonitrile with reductions in edema of 32, 30, 46, and 49%, respectively, represent the best candidates for subsequent study.