575433-87-3

Upstream product

• 934-60-1 6-methyl-2-pyridinecarboxylic acid 
• 98946-18-0 tert-Butyl 2,2,2-trichloroacetimidate 

Downstream Products

• 1605289-47-1 N,N′-(2-nitrobenzenesulfonamide)-N,N″-[[6-(methoxycarbonyl)-pyridin-2-yl]methyl]-1-(p-nitrobenzyl)-1,2-diaminoethane 
• 1605289-48-2 N,N′-[[6-(methoxycarbonyl)pyridin-2-yl]methyl]-1-(p-nitrobenzyl)-1,2-diaminoethane 
• 1332367-75-5 N,N′-[[(6-carboxylato)pyridin-2-yl]methyl]-1-(p-benzylisothiocyanato)-1,2-diaminoethane 
• 1605289-49-3 N,N′-[(tert-butoxycarbonyl)methyl]-N,N′-[[(6-tert-butoxycarbonyl)pyridin-2-yl]methyl]-1-(p-nitrobenzyl)-1,2-diaminoethane 
• 1450624-97-1 N,N′-[(carboxylato)methyl]-N,N′-[[(6-carboxylato)pyridin-2-yl]methyl]-1-(p-benzylisothiocyanato)-1,2-diaminoethane 
• 1605289-43-7 N,N′-(2-nitrobenzenesulfonamide)-[N,N′-[6-(tert-butoxycarbonyl)pyridin-2-yl]methyl]-1,2-diaminoethane 

Relevant academic research and scientific papers

Synthesis and Coordination Chemistry of Hexadentate Picolinic Acid Based Bispidine Ligands

The synthesis and CuII, NiII, ZnII, CoII, and GaIII coordination chemistry of the two isomeric hexadentate N5O ligands 6-[[9-hydroxy-1,5-bis(methoxycarbonyl)-7-methyl-6,8-bis(pyridin-2-yl)-3,7-diazabicyclo[3.3.1]nonan-3-yl]methyl]picolinic acid (Hbispa1a) and 6-[[9-hydroxy-1,5-bis(methoxycarbonyl)-7-methyl-2,4-bis(pyridin-2-yl)-3,7-diazabicyclo[3.3.1]nonan-3-yl]methyl]picolinic acid (Hbispa1b), picolinic acid-appended bispidines, are described. The two ligands are highly preorganized for octahedral coordination geometries and are particularly well suited for tetragonal symmetries, i.e., for Jahn-Teller labile ground states. This is confirmed by all data presented: solid-state structures, solution spectroscopy, electrochemistry, and CuII complex stabilities. Differences in the preorganization of the two isomers for the Jahn-Teller labile CuII centers are thoroughly analyzed on the basis of the crystal structures and an angular-overlap-model-based ligand-field analysis.

Modular syntheses of H4octapa and H2dedpa, and yttrium coordination chemistry relevant to 86Y/90Y radiopharmaceuticals

The ligands H2dedpa, H4octapa, p-SCN-Bn-H 2dedpa, and p-SCN-Bn-H4octapa were synthesized using a new protection chemistry approach, with labile tert-butyl esters replacing the previously used methyl esters as pr

BIFUNCTIONAL CHELATING AGENTS

A bifunctional chelating agent of the formula (I): wherein the variables R1, R1 , Q1, Q2 and M are as defined in the description of the present application. Also described is a complex of the above chelating age