57548-58-0Relevant academic research and scientific papers
Preparation method of sodium o-methylphenoxyacetate in synthesis process of sodium 2-methyl-4-chlorophenoxyacetate
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Paragraph 0067; 0070-0090, (2021/08/14)
The invention relates to a preparation method of sodium o-methylphenoxyacetate in a synthesis process of sodium 2-methyl-4-chlorophenoxyacetate. The invention provides a preparation method of sodium o-methylphenoxyacetate, which comprises the following steps of: reacting o-cresol with sodium hydroxide to obtain a sodium o-cresol solution, reacting chloroacetic acid with sodium hydroxide to obtain a sodium chloroacetate solution, and reacting the sodium o-cresol with sodium chloroacetate under the condition of a catalyst to obtain the sodium o-methylphenoxyacetate. The catalyst is added in the preparation process, so that the reaction temperature and the decomposition rate of sodium chloroacetate can be effectively reduced, the conversion rate of o-cresol is improved, the problems of difficulty in later phenol-containing wastewater treatment and high energy consumption caused by low conversion rate of o-cresol are solved, and the preparation process is effectively simplified. Meanwhile, the sodium o-methylphenoxyacetate prepared by the preparation method is relatively high in purity and yield.
Continuous preparation method and preparation system of 2-methyl-4-chlorophenoxyacetic acid
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Page/Page column 0021; 0024; 0035-0061, (2022/01/10)
The present invention belongs to the technical field of 2-methyl-4-chlorophenoxyacetic acid, specifically relates to a continuous preparation method and preparation system of 2-methyl-4-chlorophenoxyacetic acid. The continuous preparation method of 2-methyl-4-chlorophenoxyacetic acid comprising: the o-cresol and the alkali solution into a salt reaction, to obtain a phenol salt solution; after the chloroacetic acid is added to the phenol salt solution for condensation reaction, the reaction solution is evaporated to obtain o-toluoxyacetate; organic solvent and acid are added to the o-toluoxyacetate, after acidification reaction, the reaction mixture is separated from the intermediate solution; chlorine is introduced into the intermediate solution, and after the chlorination reaction, the product solution is separated After crystal separation and drying of the product solution, 2-methyl-4-chlorophenoxyacetic acid was prepared. By configuring an automated control system through continuous production, human resources can be greatly reduced.
Finding new elicitors that induce resistance in rice to the white-backed planthopper Sogatella furcifera
He, Xingrui,Yu, Zhaonan,Jiang, Shaojie,Zhang, Peizhi,Shang, Zhicai,Lou, Yonggen,Wu, Jun
supporting information, p. 5601 - 5603 (2015/11/17)
Herein we report a new way to identify chemical elicitors that induce resistance in rice to herbivores. Using this method, by quantifying the induction of chemicals for GUS activity in a specific screening system that we established previously, 5 candidate elicitors were selected from the 29 designed and synthesized phenoxyalkanoic acid derivatives. Bioassays confirmed that these candidate elicitors could induce plant defense and then repel feeding of white-backed planthopper Sogatella furcifera.
Synthesis and structure-activity relationship of ethacrynic acid analogues on glutathione-s-transferase P1-1 activity inhibition
Zhao, Guisen,Yu, Tao,Wang, Rui,Wang, Xiaobing,Jing, Yongkui
, p. 4056 - 4062 (2007/10/03)
Ethacrynic acid (EA) is a glutathione-s-transferase π (GSTP1-1) inhibitor. Fifteen of EA analogues were designed and synthesized and their inhibition on GSTP1-1 activity was tested in lysate of human leukemia HL-60 cells. These compounds were synthesized
