575504-30-2

Basic information

• Product Name: 1H-Indene-4-carboxaldehyde,2,3-dihydro-7-hydroxy-6-methyl-(9CI)
• Synonyms: 1H-Indene-4-carboxaldehyde,2,3-dihydro-7-hydroxy-6-methyl-(9CI);7-HYDROXY-6-METHYL-2,3-DIHYDRO-1H-INDENE-4-CARBALDEHYDE
• CAS NO: 575504-30-2
• Molecular Formula: C₁₁H₁₂O₂
• Molecular Weight: 176.214
• Product Categories: CYCLOHEXANE
• Mol File: 575504-30-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 325°C at 760 mmHg
• Flash Point: 137.9°C
• Appearance: /
• Density: 1.216g/cm³
• Vapor Pressure: 0.000125mmHg at 25°C
• Refractive Index: 1.635
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1H-Indene-4-carboxaldehyde,2,3-dihydro-7-hydroxy-6-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indene-4-carboxaldehyde,2,3-dihydro-7-hydroxy-6-methyl-(9CI)(575504-30-2)
• EPA Substance Registry System: 1H-Indene-4-carboxaldehyde,2,3-dihydro-7-hydroxy-6-methyl-(9CI)(575504-30-2)

Safety Data

• Hazardous Substances Data: 575504-30-2(Hazardous Substances Data)

Usage

General Description

1H-Indene-4-carboxaldehyde,2,3-dihydro-7-hydroxy-6-methyl-(9CI) is a chemical compound with the molecular formula C11H12O2. It is a derivative of indene and carboxaldehyde, featuring both a hydroxy group and a methyl group. 1H-Indene-4-carboxaldehyde,2,3-dihydro-7-hydroxy-6-methyl-(9CI) is used in various chemical and pharmaceutical applications, often as an intermediate in the synthesis of other organic compounds. Its specific properties and uses may vary depending on the intended application, but it is generally considered to be a versatile and valuable building block for organic synthesis. The compound's structure and reactivity make it suitable for a wide range of reactions and transformations in the production of pharmaceuticals, agrochemicals, and other fine chemicals.

InChI:InChI=1/C11H12O2/c1-7-5-8(6-12)9-3-2-4-10(9)11(7)13/h5-6,13H,2-4H2,1H3

Upstream product

• 95-48-7 ortho-cresol 
• 1641-41-4 4-indanol 
• 1092553-17-7 4-hydroxy-5-methyl-2,3-dihydro-1H-inden-1-one 
• 1092553-18-8 4-hydroxy-2,3-dihydro-1H-indene-5-carboxaldehyde 
• 140840-98-8 8-methyl-3,4-dihydrocoumarin 
• 1807-36-9 8-methylcoumarin 
• 824-42-0 2-methoxy-3-methylbenzaldehyde 
• 20294-31-9 5-methyl-2,3-dihydro-1H-inden-4-ol 
• 100-97-0 hexamethylenetetramine 

Downstream Products

• 1092553-16-6 7-Methoxy-6-methyl-indan-4-carboxaldehyde 
• 1092551-88-6 3-{4-[(7-hydroxy-6-methylindan-4-yl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}propionic acid 

Relevant articles and documents

METHODS OF PRODUCING PYRAZOLE COMPOUNDS

The present invention is directed to methods of producing substituted pyrazole based compounds through novel intermediates and unique processes for preparing such intermediates which enables synthesis of final product through commercially viable route of synthesis. The present invention is also directed to novel methods of producing substituted pyrazole based thyroid like compounds, and solid forms of 3-{4-[(7-hydroxy-6-methyl-indan-4-yl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-propanoic acid, its pharmaceutical compositions, and methods of preparation thereof.

Novel Compounds

The present invention discloses a novel thyroid like compounds of formula (I), wherein R1 R2, R3, R4 and Z are as defined in the specification, method for its preparation, composition containing such compounds and use of such compounds and composition as medicament. Further, compounds of formula (I) has significantly low binding affinity to thyroid receptors and thus considerably devoid of thyrotoxic effects. The invention also relates to the use of the compound of formula (I) for the preparation of a medicament for treating various disease conditions such as obesity, dyslipidemia, metabolic syndrome and co-morbidities associated with metabolic syndrome.

NOVEL THYROID HORMONE RECEPTOR LIGAND, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND USE THEREOF

The present invention provides a compound represented by general formula (I): . or pharmaceutically acceptable salts thereof, wherein W is O, S(O)m, CH2 and the like: R1 is halogen, lower alkyl, halo-lower alkyl, CN and th