57568-38-4

Upstream product

• 41876-58-8 1-cyclohexyl-3-methoxybenzene 
• 7646-78-8 tin(IV) chloride 
• 75-36-5 acetyl chloride 
• 579-74-8 2-Methoxyacetophenone 
• 110-82-7 cyclohexane 

Downstream Products

• 57568-39-5 4-cyclohexyl-2-(methoxy)thionophenylacetomorpholide 
• 57568-36-2 4'-cyclohexyl-2'-hydroxy-phenylacetic acid 
• 57568-40-8 4-cyclohexyl-2-methoxyphenylacetic acid 
• 66883-53-2 (4-Cyclohexyl-2-hydroxy-5-methyl-phenyl)-acetic acid 
• 60987-05-5 2-(5-chloro-4-cyclohexyl-2-hydroxyphenyl)-acetic acid 
• 66883-46-3 5-bromo-4-cyclohexyl-2-hydroxyphenylacetic acid 
• 66883-45-2 3-bromo-4-cyclohexyl-2-hydroxyphenylacetic acid 
• 66883-50-9 5-Chloro-4-cyclohexyl-2-hydroxy-α-methyl-phenylacetic acid 
• 66883-44-1 4-cyclohexyl-2-hydroxy-5-nitrophenylacetic acid 
• 57568-37-3 6-cyclohexyl-2,3-dihydrobenzofuran-2-one 
• 60986-91-6 7-bromo-6-cyclohexyl-2,3-dihydrobenzofuran-2-one 
• 60986-96-1 6-cyclohexyl-2,3-dihydro-5-methylbenzofuran-2-one 
• 79380-80-6 4-cyclohexyl-2-methoxy-5-methylphenylacetic acid 
• 79380-78-2 4-cyclohexyl-5-formyl-2-methoxyphenylacetic acid 

Relevant academic research and scientific papers

Nickel-Catalyzed, para-Selective, Radical-Based Alkylation of Aromatic Ketones

A direct, para-selective, radical-based alkylation of aromatic ketones with alkanes has been developed using a nickel catalyst with oxamide as the ligand. Acetophenones bearing electron-withdrawing substituents were functionalized directly with simple alkanes with high para-selectivity while acetophenones with electron-donating groups were mainly para-functionalized. A mechanistic study indicated that C-H bond activation of the aromatic ring may be the rate-determining step of the reaction.

Preparation method of 4-cycloalkylacetophenone derivatives

The invention discloses a preparation method of 4-cycloalkylacetophenone derivatives, and belongs to the technical field of organic compounds. A 2-substituted acetophenone derivative or a 3-substituted acetophenone derivative is used as an initiator, so raw materials are easy to obtain and have many kinds; and the 4-substituted cycloalkyl acetophenone derivatives obtained by using the method are various, can be directly used, and can also be used in other further reactions. The preparation method has the advantages of simplicity in reaction operation and post-treatment, high yield, and no generation of a large amount of metal salts, is a green method with high atom economy, and is suitable for large-scale production.

2,3-Dihydrobenzofuran-2-ones: A New Class of Highly Potent Antiflammatory Agents

A series of 2,3-dihydrobenzofuran-2-one analogues of the mold metabolite wortmannin, which is a powerful antiimflammatory compound, was synthesized.Most of these compounds were tested for their ability to inhibit the carrageenin paw edema and the adjuvant

Organic compounds

This invention provides compounds of formula I, STR1 wherein R1 is alkyl of 1 to 10 carbon atoms, cycloalkyl of 3 to 8 carbon atoms or phenyl, and R2 is hydrogen or alkyl of 1 to 4 carbon atoms, Useful as anti-phlogistics, anti-pyret