57591-01-2Relevant academic research and scientific papers
Bronsted acid catalyzed asymmetric SN2-Type O-alkylations
Coric, Ilija,Kim, Ji Hye,Vlaar, Tjostil,Patil, Mahendra,Thiel, Walter,List, Benjamin
supporting information, p. 3490 - 3493 (2013/05/09)
Bridging the gap: Bronsted acids catalyze an intramolecular S N2-type alkylation of alcohols with ethers by bridging a pentacoordinate transition state, thus simultaneously activating both the leaving group and nucleophile (see scheme). Density functional calculations provide detailed insight into the course of the reaction and the transition-state structure.
Synthesis and Structure - Activity Relationships of Sweet 2-Benzoylbenzoic Acid Derivatives
Arnoldi, Anna,Bassoli, Angela,Borgonovo, Gigliola,Merlini, Lucio,Morini, Gabriella
, p. 2047 - 2054 (2007/10/03)
Twenty-four analogues of the sweet compound 2-(4-methoxybenzoyl)benzoic acid 1 were synthesized and tasted. The structure-sweet taste relationships were studied by means of principal component analysis and by comparison with the existing sweet receptor models. Three possible glucophores were identified, which could correspond to the sites B, E1, and E2 of the Tinti - Nofre model. Some similarities between this class of compounds and isovanillic sweeteners were found.
4,5 Dihydroimidazole compounds which have useful pharmaceutical utility
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, (2008/06/13)
A compound of formula (I): STR1 or a pharmaceutically acceptable salt, ester or amide thereof, or a pharmaceutically acceptable solvate thereof, wherein: Z represents a residue of a substituted or unsubstituted aryl group, A1 represents a subst
