57598-32-0

Usage

Uses

Used in Organic Chemistry Research:
2-(2,3-dimethoxyphenyl)-4,4-dimethyl-4,5-dihydrooxazole is used as a research compound for the synthesis of new organic compounds. Its unique structure and functional groups make it valuable for exploring novel reactions and developing innovative synthetic pathways.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 2-(2,3-dimethoxyphenyl)-4,4-dimethyl-4,5-dihydrooxazole is used as a starting material or intermediate in the development of new drugs. Its heterocyclic nature and the presence of dimethoxy and dimethyl groups may impart specific biological activities or improve the pharmacokinetic properties of the resulting drug candidates.
Used in Medicinal Chemistry:
2-(2,3-dimethoxyphenyl)-4,4-dimethyl-4,5-dihydrooxazole is utilized as a building block in medicinal chemistry for the design and synthesis of bioactive molecules. Its structural features can be exploited to modulate the activity of target proteins or enzymes, leading to the discovery of potential therapeutic agents.
Used in Chemical Synthesis:
As a versatile chemical compound, 2-(2,3-dimethoxyphenyl)-4,4-dimethyl-4,5-dihydrooxazole is employed in various chemical synthesis processes. Its reactivity and functional groups can be harnessed to produce a range of chemical products, including specialty chemicals, agrochemicals, and materials.

Upstream product

• 7169-06-4 2,3-dimethoxybenzoyl chloride 
• 1521-38-6 2,3-dimethoxybenzoic acid 
• 144034-41-3 N-(1-hydroxy-2-methylpropan-2-yl)-2,3-dimethoxybenzamide 

Downstream Products

• 64957-73-9 4,4,4',4'-tetramethyl-4,5,4',5'-tetrahydro-2,2'-(3,3'-dimethoxy-2,2'-butane-1,4-diyl-diphenyl)-bis-oxazole 
• 64957-72-8 2-(3-methoxy-2-trimethylsilanyl-phenyl)-4,4-dimethyl-4,5-dihydro-oxazole 
• 65000-03-5 4,4,4',4'-tetramethyl-4,5,4',5'-tetrahydro-2,2'-(6,6''-dimethoxy-p-terphenyl-2,2''-diyl)-bis-oxazole 
• 64957-77-3 3-Methoxy-2-(3-phenyl-propyl)-benzoic acid 
• 63478-17-1 N-tert-butyl-2-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-6-methoxy-aniline 
• 63478-15-9 2-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-N,N-diethyl-6-methoxy-aniline 
• 57598-42-2 2-(2-ethyl-3-methoxy-phenyl)-4,4-dimethyl-4,5-dihydro-oxazole 
• 57598-51-3 2-Ethyl-3-Methoxybenzoic Acid 
• 72623-17-7 2-(2-Methyl-3-methoxyphenyl)-4,4-dimethyl-2-oxazoline 
• 55289-06-0 3-methoxy-2-methylbenzoic acid 
• 57598-43-3 2-(2-tert-butyl-3-methoxy-phenyl)-4,4-dimethyl-4,5-dihydro-oxazole 
• 57598-52-4 2-tert.Butyl-3-methoxybenzoesaeure 
• 143123-58-4 2-(3-Methoxy-2-vinylphenyl)-4,4-dimethyl-2-oxazoline 
• 64957-80-8 3-methoxy-2-vinylbenzoic acid 

Relevant academic research and scientific papers

Structural interrogation of benzosuberene-based inhibitors of tubulin polymerization

The discovery of 3-methoxy-9-(3′,4′,5′-trimethoxyphenyl)-6,7-dihydro-5H-benzo[7]annulen-4-ol (a benzosuberene-based analogue referred to as KGP18) was originally inspired by the natural products colchicine and combretastatin A-4 (CA4). The relative struct

Synthesis of antimicrobial natural products targeting FtsZ: (+)-totarol and related totarane diterpenes

(Equation Presented). An efficient, convergent synthesis of totarol by a diastereoselective epoxide/alkene/arene bicyclization is described. The reported synthesis enables the preparation of related diterpenes totaradiol and totarolone as well as previously unavailable derivatives that exhibit comparable inhibition of the bacterial cell division protein FtsZ.

Photochromic properties of new benzoindene-fused 2H-chromenes

The synthesis and the photochromic properties of new photochromic 6,7- and 7,8-benzoindene annellated benzopyrans are described. When compared to parent indeno-fused 2H-chromenes (2H-[1]benzopyrans), compounds 10 and 12 exhibit a significant bathochromic shift of maximum-absorption wavelength, an increase in the colorability, and similar fading rates.

Application of an intramolecular heck reaction for the construction of the balanol aryl core structure

The highly functionalized aryl core structure of balanol has been synthesized employing a regioselective intramolecular Heck reaction as the key step. This approach can potentially lead to new types of analogues of the potent PKC inhibitor.

Synthesis of Substituted Fluorenones and Substituted 3',3'-Dichlorospiro and Their Reactivities

Several novel 9-fluorenones were synthesized and were used as precursors in an attempt to prepare unique substituted 3',3'-dichlorospiro.Several of the thiiranes were unstable and desulfurized during their preparation (7a-d, 11, 12). 3',3'-Dichloro(2,5-dimethoxyspiro (7f) was prepared along with 2,2-dichloro-3,3-bis(4-methoxyphenyl)thiirane (16), and 3',3'-dichloro-10,11-dihydrospirocycloheptane-5,2'-thiirane> (17) all of which were stable at room temperature.A study of the reactivity of fluorenyl-substituted thiiranes and other related thiiranes showed that the extent of aromaticity of the substituents at the 3-position of the thiiranes influences their stabilities.

Carbacyclin analogs

Carbacyclin analogs that exhibit platelet aggregation inhibition activity and other biological activites common to structurally related prostacyclins are provided.