57614-92-3

Basic information

• Product Name: 4-(4-Piperidyl)-1-butanol
• Synonyms: 4-(4-Piperidyl)-1-butanol;4-(piperidin-4-yl)butan-1-ol;4-Piperidinebutanol
• CAS NO: 57614-92-3
• Molecular Formula: C₉H₁₉NO
• Molecular Weight: 157.25326
• Mol File: 57614-92-3.mol
• Article Data: 6

Chemical Properties

• Melting Point: 57-60 °C
• Boiling Point: 122 °C(Press: 12 Torr)
• Appearance: /
• Density: 0.921±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 15.18±0.10(Predicted)
• CAS DataBase Reference: 4-(4-Piperidyl)-1-butanol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Piperidyl)-1-butanol(57614-92-3)
• EPA Substance Registry System: 4-(4-Piperidyl)-1-butanol(57614-92-3)

Safety Data

• Hazardous Substances Data: 57614-92-3(Hazardous Substances Data)

Usage

General Description

4-(4-Piperidyl)-1-butanol, also known as piperidin-4-yl-butanol, is a chemical compound that belongs to the class of alcohols. It is a clear, colorless liquid with a faint odor and is soluble in water. 4-(4-Piperidyl)-1-butanol has a molecular formula of C9H19NO and a molecular weight of 157.25 g/mol. It is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals due to its versatile reactivity. Additionally, 4-(4-Piperidyl)-1-butanol has a variety of applications in industries such as fragrance and flavor, and it is also used as a chiral building block in the synthesis of optically active compounds. Its chemical structure and properties make it a valuable component in the production of diverse products across various sectors.

Upstream product

• 5264-15-3 4-(4-pyridinyl)butan-1-ol 
• 372195-85-2 4-butylpiperidine hydrochloride 

Downstream Products

• 142355-83-7 4-(1-tert-butoxycarbonylpiperidin-4-yl)-butan-1-ol 
• 1041756-57-3 [4-(4-aminobutyl)-1-piperidinyl](phenyl)methenone 
• 1296137-14-8 2-{4-[1-(phenylcarbonyl)piperidin-4-yl]butyl}-1H-isoindole-1,3(2H)-dione 
• 1360619-08-4 (2E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-{3-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]phenyl}prop-2-enamide hydrochloride 
• 1041756-51-7 C₁₆H₂₃NO₂ 
• 318508-02-0 4-(N-benzyl-4'-piperidinyl)-1-butanol 
• 151097-70-0 3-(1-benzylpiperidin-4-yl)propan-1-amine 
• 885268-87-1 4-(3-N-tert-butoxycarbonylaminopropyl)piperidine 
• 142355-81-5 tert-butyl 4-(4-bromobutyl)piperidine-1-carboxylate 
• 1338213-12-9 (E)-1-(4-(1-benzoylpiperidin-4-yl)butyl)-2-cyano-3-(pyridin-4-yl)guanidine 
• 201034-98-2 tert-butyl 4-(4-aminobutyl)piperidine-1-carboxylate 

Relevant articles and documents

PIPERIDINE DERIVATIVES FOR USE IN THE TREATMENT OF PANCREATIC CANCER

The present invention relates to novel piperidine derivatives having better cell growth inhibitory activities toward cancer cell cultures and, more particularly, PANC-1 cancer cell cultures than FK866. Accordingly, the present invention relates to compoun

Platinum-Catalyzed, Terminal-Selective C(sp3)-H Oxidation of Aliphatic Amines

This Communication describes the terminal-selective, Pt-catalyzed C(sp3)-H oxidation of aliphatic amines without the requirement for directing groups. CuCl2 is employed as a stoichiometric oxidant, and the reactions proceed in high yield at Pt loadings as low as 1 mol%. These transformations are conducted in the presence of sulfuric acid, which reacts with the amine substrates in situ to form ammonium salts. We propose that protonation of the amine serves at least three important roles: (i) it renders the substrates soluble in the aqueous reaction medium; (ii) it limits binding of the amine nitrogen to Pt or Cu; and (iii) it electronically deactivates the C-H bonds proximal to the nitrogen center. We demonstrate that this strategy is effective for the terminal-selective C(sp3)-H oxidation of a variety of primary, secondary, and tertiary amines.

Synthesis of a C-iminoribofuranoside analog of the nicotinamide phosphoribosyltransferase (NAMPT) inhibitor FK866

FK866 (also named APO866 or WK175) is a potent NAMPT inhibitor being evaluated (Phase II) as a potential anticancer drug. The preparation of the C-iminoribofuranoside analog (2E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-{3- [(2S,3S,4R,5R)-3,4-dihydroxy-5-(h