1360619-08-4Relevant articles and documents
Synthesis of a C-iminoribofuranoside analog of the nicotinamide phosphoribosyltransferase (NAMPT) inhibitor FK866
Gillig, Annabelle,Majjigapu, Somi Reddy,Sordat, Bernard,Vogel, Pierre
, p. 34 - 42 (2012/03/07)
FK866 (also named APO866 or WK175) is a potent NAMPT inhibitor being evaluated (Phase II) as a potential anticancer drug. The preparation of the C-iminoribofuranoside analog (2E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-{3- [(2S,3S,4R,5R)-3,4-dihydroxy-5-(h