5771-32-4

Basic information

• Product Name: spiro[2.4]heptan-7-one
• Synonyms: spiro[2.4]heptan-7-one;Spiro[2.4]heptan-4-one
• CAS NO: 5771-32-4
• Molecular Formula: C7H10O
• Molecular Weight: 110.15
• Mol File: 5771-32-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 175.3°Cat760mmHg
• Flash Point: 52.9°C
• Appearance: /
• Density: 1.05g/cm³
• Refractive Index: 1.551
• CAS DataBase Reference: spiro[2.4]heptan-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: spiro[2.4]heptan-7-one(5771-32-4)
• EPA Substance Registry System: spiro[2.4]heptan-7-one(5771-32-4)

Safety Data

• Hazardous Substances Data: 5771-32-4(Hazardous Substances Data)

Usage

General Description

Spiro[2.4]heptan-7-one is a chemical compound with a spirocyclic structure. It belongs to the class of ketones and is commonly used in the synthesis of various pharmaceuticals and agrochemicals. It is also known for its use as a flavor and fragrance ingredient in the food and beverage industry. The compound is characterized by its unique seven-membered ring structure, which makes it an important building block for the development of new chemical compounds. Spiro[2.4]heptan-7-one is considered to be a versatile and valuable chemical compound with a wide range of industrial applications.

InChI:InChI=1/C10H17N5O3/c11-9-8(13-18-14-9)10(16)12-2-1-3-15-4-6-17-7-5-15/h1-7H2,(H2,11,14)(H,12,16)

Upstream product

• 6749-50-4 spiro<2,4>heptan-4-ol 
• 694-28-0 2-chlorocyclopentanone 
• 70775-39-2 dimethylsulfoxonium methylide 
• 75-21-8 oxirane 
• 15090-41-2 diethyl 2-oxocyclopentylphosphonate 
• 1191-95-3 cyclobutanone 
• 54022-19-4 diazocyclopropane 
• 10575-90-3 N-nitroso-N-cyclopropylurea 
• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 
• 106-93-4 ethylene dibromide 
• 33229-08-2 2-(β-bromoethyl)-2-carboethoxycyclopentanone 
• 1106-21-4 2,2-Bis-tosyloxymethyl-cyclopentan-1-on 
• 933-34-6 2,2-bis(bromomethyl)cyclopentan-1-one 
• 89892-90-0 2-(β-bromoethyl)cyclopentanone 

Downstream Products

• 52708-23-3 Spiro<2.4>hept-4-en 
• 6749-50-4 spiro<2,4>heptan-4-ol 
• 93069-40-0 5-phenylthiospiro<2.4>hept-5-en-4-one 
• 93069-43-3 5-phenylthio-6-<3-tert-butyldimethylsilyloxy-(E)-1-octenyl>-spiro<2.4>heptan-4-one 
• 5771-41-5 5,5-Bis-tosyloxymethyl-spiro<2.4>heptan-4-on 
• 106422-06-4 5-benzylidene-spiro[2.4]heptan-4-one 

Relevant articles and documents

RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN, POLYMERIC COMPOUND, AND COMPOUND

A resist composition including a resin component having a structural unit derived form a compound represented by formula (a0-1) (in the formula, W represents a polymerizable group-containing group; Ra01 is a group which is bonded to Ra03 to form an aliphatic cyclic group, or bonded to Ra04 to form an aliphatic cyclic group; Ra02 represents a hydrocarbon group which may have a substituent; Ra03 is a hydrogen atom or a monovalent organic group in the case where Ra01 is not bonded thereto; Ra04 is a hydrogen atom or a monovalent organic group in the case where Ra01 is not bonded thereto; and Ra05 to Ra07 each independently represents a hydrogen atom or a monovalent organic group).

Synthesis of gem-dinitro compounds with a three-membered cycle

A reaction was studied between nitrogen pentoxide in chloroform and oximes of cyclic ketones, derivatives of bicyclo[3.1.0]hexane, bicyclo[4.1.0]heptane, spiro[2.4]heptane, spiro[2.5]octane, resulting in the corresponding gem-dinitro compounds.

Synthons for Syntheses of Spiroheptane Analogues of Prostaglandins

Methods for the preparation of synthons for syntheses of spiroheptane analogues of prostaglandins are described.Two of them (1a and 1b) enable the syntheses of 11-deoxy-type compounds and were prepared from spiroheptan-4-one (3) which after transformation into the 5-phenylthio-α, β-unsaturated ketone 5 was subjected to conjugate addition of organocuprate reagent 6.The third synthon (2) - a potential intermediate in syntheses of complete spiroheptane analogues of prostaglandins-was prepared from the bicyclic ketone 10 by Baeyer-Villiger oxidation follo wed by epoxidation. - Keywords: Prostaglandin analogues; Spiroheptan-4-ones; 2H-Cyclopentafuran-2-ones; Desulfurization; Conjugate addition of cuprate