57718-18-0

Usage

Uses

Used in Pharmaceutical Synthesis:
1-PHENYL-1-NONYNE is used as a key building block for the synthesis of pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique structure allows for the creation of a wide range of medicinal compounds with specific therapeutic properties.
Used in Agrochemical Production:
In the agrochemical industry, 1-PHENYL-1-NONYNE is utilized as a starting material for the synthesis of various agrochemicals, such as pesticides and herbicides. Its incorporation aids in the development of effective products for agricultural applications.
Used in Specialty Chemicals Synthesis:
1-PHENYL-1-NONYNE is employed as a building block in the synthesis of specialty chemicals, which are used in diverse industries such as plastics, coatings, and fragrances. Its versatility in chemical reactions enables the production of tailored specialty chemicals with specific properties.
Used as a Cross-Coupling Reagent in Organic Synthesis:
1-PHENYL-1-NONYNE serves as a cross-coupling reagent in organic synthesis, facilitating the formation of carbon-carbon bonds. This role is crucial in the construction of complex organic molecules and contributes to the advancement of organic chemistry.
Used as a Ligand in Catalytic Reactions:
In catalytic reactions, 1-PHENYL-1-NONYNE is used as a ligand, enhancing the efficiency and selectivity of the catalytic process. Its presence can improve the performance of catalysts, leading to more effective and environmentally friendly chemical transformations.

Upstream product

• 591-51-5 phenyllithium 
• 189343-67-7 1-(benzotriazol-1-yl)-1-phenoxy-2-nonanone p-tosylhydrazone 
• 106-32-1 octanoic acid ethyl ester 
• 189343-54-2 1-Benzotriazol-1-yl-1-phenoxy-nonan-2-one 
• 6738-06-3 phenylethynylmagnesium bromide 
• 4282-40-0 1-Iodoheptane 
• 536-74-3 phenylacetylene 
• 142-82-5 n-heptane 
• 5324-64-1 2-(benzenesulfonyl)ethynylbenzene 

Downstream Products

• 42036-73-7 1-((E)-non-1-enyl)benzene 
• 111735-48-9 (Z)-1-(non-1-enyl)benzene 
• 1004539-65-4 1,1-dibromo-2-heptyl-1,3,4-triphenyl-triphenylene 

Relevant academic research and scientific papers

Copper-Catalyzed Intermolecular Alkynylation and Allylation of Unactivated C(sp3)-H Bonds via Hydrogen Atom Transfer

We describe Cu-catalyzed intermolecular alkynylation and allylation of unactivated C(sp3)-H bonds with singly occupied molecular orbital-philes (SOMO-philes) via hydrogen atom transfer (HAT). Employing N-fluoro-sulfonamide as a HAT reagent, a set of subst

Mild and phosphine-free iron-catalyzed cross-coupling of nonactivated secondary alkyl halides with alkynyl grignard reagents

A simple protocol for iron-catalyzed cross-coupling of nonactivated secondary alkyl bromides and iodides with alkynyl Grignard reagents at room temperature has been developed. A wide range of secondary alkyl halides and terminal alkynes are tolerated to a

A Novel Transformation of Esters to Alkynes with 1-Substituted Benzotriazoles

Reactions of lithio benzotriazol-1-yl derivatives 2, 11, and 25 with aromatic and aliphatic esters 3, 12, and 26 gave α-(benzotriazol-l-yl) ketones 4, 13, and 27, respectively, in high yields. Alternatively, α-(benzotriazol-l-yl) ketones 22 can be accessed by the reaction of α-(benzotriazol-1-yl) esters 20 with Grignard reagents. Condensation of 4, 13, 22, and 27 with (p-toluenesulfonyl)hydrazine provided p-tosylhydrazones 5, 14, 21, and 28. Treatment of hydrazones 5, 21, and 28 with n-butyllithium in diethyl ether resulted in the elimination of the tosyl group, dinitrogen, and benzotriazolyl group to afford the corresponding acetylenes 9, 23, and 29 in good yields. When α-(benzotriazol-l-yl) 1-α-phenoxy hydrazones 14 were treated with methyllithium, n-butyllithium, or phenyllithium, alkynes 18 were obtained, in which phenoxy groups were replaced by the lithium reagents.