57763-82-3Relevant academic research and scientific papers
Catalytic asymmetric hydrogenation of N-Boc-imidazoles and oxazoles
Kuwano, Ryoichi,Kameyama, Nao,Ikeda, Ryuhei
supporting information; experimental part, p. 7312 - 7315 (2011/06/24)
Substituted imidazoles and oxazoles were respectively hydrogenated into the corresponding chiral imidazolines and oxazolines (up to 99% ee). The highly enantioselective hydrogenation was achieved by using the chiral ruthenium catalyst, which is generated
SYNTHESIS OF CHIRAL 1,2-DIAMINES
Bruni, Elena,Cardillo, Giuliana,Orena, Mario,Sandri, Sergio,Tomasini, Claudia
, p. 1679 - 1682 (2007/10/02)
(1'S,5R,S)-(1'-phenyleth-1'-yl)-5-iodomethyl-imidazolines 4a, b have been synthesised and easily resolved by silica gel chromatography.The correlation between the configuration and the 1H-NMR chemical shifts allows to assign the configuration at the C-5 of these intermediates.Each pure diastereomer has been converted to R(-)- and to S(+)-1,2-propyldiamine, respectively.
