577975-53-2Relevant academic research and scientific papers
ISOXAZOLE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME
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Page 11-12, (2008/06/13)
The present invention provides isoxazole derivatives represented by the following formula (I): (wherein R1 represents a hydrogen atom, C1 - C20 hydrocarbon group or ? C(=O)OR1a (wherein R1a represents
Molecular sieve (MS 4A) promoted cyclocondensation of hindered, aromatic nitrile oxides and cyclic diketones under mild conditions
Matsuura, Tomoo,Bode, Jeffrey W.,Hachisu, Yoshifumi,Suzuki, Keisuke
, p. 1746 - 1748 (2007/10/03)
Molecular sieves (MS 4A) serve as efficient promoters for the cyclocondensation of stable, hindered nitrile oxides and a variety of cyclic diketones to afford fused isoxazoles in good yield. The operational simplicity and remarkably mild reaction conditions compliment our amine-promoted cyclocondensation conditions and demonstrate broad substrate scope.
Amine-promoted cyclocondensation of highly substituted aromatic nitrile oxides with diketones
Bode, Jeffrey W.,Hachisu, Yoshifumi,Matsuura, Tomoo,Suzuki, Keisuke
, p. 3555 - 3558 (2007/10/03)
Base-promoted cyclocondensation of hindered nitrile oxides and cyclic diketones affords highly functionalized, sterically-encumbered isoxazole products in good yield. The mild reaction conditions (NEt3, EtOH) are tolerant to a wide variety of f
