577991-52-7

Upstream product

• 5610-49-1 N-butylpiperazine 
• 459-57-4 4-fluorobenzaldehyde 
• 92-54-6 4-phenyl-1-piperazine 
• 80944-47-4 4-n-butyl-1-phenylpiperazine 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1246249-17-1 2-[4-(4-butylpiperazin-1-yl)phenyl]-5,7-dimethoxyquinazolin-4(3H)-one 
• 112898-93-8 4-(4-Butyl-piperazin-1-yl)-benzaldehyde oxime 
• 112898-99-4 N-butyl-N'-<4-(1-hydroxyhexyl)phenyl>piperazine 

Relevant academic research and scientific papers

Design, synthesis, and bioactivity investigation of novel benzimidazole derivatives as potent urease inhibitors

Herein, we synthesized a series of novel benzimidazole derivatives 5a–k and screened their bioactivity as potent urease inhibitors. The structure of the 5a–k was elucidated using spectroscopic technics (1H-NMR, 13C-NMR, MS), elementa

Anti-inflammatory agents

Disclosed are novel compounds that are useful in regulating the expression of interleukin-6 (IL-6) and/or vascular cell adhesion molecule-1 (VCAM-1), and their use in the treatment and/or prevention of cardiovascular and inflammatory diseases and related disease states, such as, for example, atherosclerosis, asthma, arthritis, cancer, multiple sclerosis, psoriasis, and inflammatory bowel diseases, and autoimmune disease(s). Also, disclosed are compositions comprising the novel compounds, as well as methods for their preparation.

Synthesis and Mesogenic Properties of N'-(4-Acylphenyl)-N-alkylpiperazines

One synthesis of N-alkyl-N'-(4-acylphenyl)piperazines and their physical properties have been studied using calorimetric, optical, and X-ray crystallography methods.The compounds exhibit only smectic phases, the higher-temperature phase being a probable s