57800-65-4Relevant academic research and scientific papers
Cobalt-Catalyzed Asymmetric Hydrogenation of 1,1-Diarylethenes
Chen, Jianhui,Chen, Chenhui,Ji, Chonglei,Lu, Zhan
supporting information, p. 1594 - 1597 (2016/05/02)
Highly enantioselective cobalt-catalyzed hydrogenation of 1,1-diarylethenes was developed by using bench-stable chiral oxazoline iminopyridine-cobalt complexes as precatalysts. A unique o-chloride effect was observed to achieve high enantioselectivity. Easy removal as well as further transformations of the chloro group make this protocol a potentially useful alternative to synthesize various chiral 1,1-diarylethanes. This process can be successfully performed under 1 atm of hydrogen at room temperature on gram scale.
Na-promoted aerobic oxidation of alcohols to ketones
Zhou, Li-Hong,Yu, Xiao-Qi,Pu, Lin
scheme or table, p. 475 - 477 (2010/09/20)
Aerobic oxidation of a number of diaryl and arylalkyl carbinols to ketones was promoted by Na in THF at room temperature with up to 99% yield. This new oxidation method is also selective with good efficiency for the oxidation of benzylic secondary alcohols but not for a primary alcohol or nonbenzylic secondary alcohols. Under nitrogen, a catalytic amount of Ni or transition metal halides such as CoCl3, FeCl3, and NiCl3 in combination with Na was also found to conduct a dehydrogenation of a secondary alcohol to the corresponding ketone in high yield at room temperature.
Glycosylated Derivatives of Benzophenone, Benzhydrol, and Benzhydril as Potential Venous Antithrombotic Agents
Bellamy, Francois,Horton, Derek,Millet, Jean,Picart, Francois,Samreth, Soth,Chazan, Jean Bernard
, p. 898 - 903 (2007/10/02)
A series of glycosylated derivatives of benzophenone, benzhydrol, and benzhydril has been synthesized and evaluated for potential activity as venous antithrombotic agents.Studies on structure-activity relationships revealed that compounds having an electr
