57931-25-6

Basic information

• Product Name: (hexyloxy)acetic acid
• Synonyms: Hexoxyacetic acid;NSC 294110;(hexyloxy)acetic acid
• CAS NO: 57931-25-6
• Molecular Formula: C₈H₁₆O₃
• Molecular Weight: 160.21084
• EINECS: 261-017-9
• Mol File: 57931-25-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 271.6°C at 760 mmHg
• Flash Point: 104.4°C
• Appearance: /
• Density: 0.991g/cm³
• Vapor Pressure: 0.00178mmHg at 25°C
• Refractive Index: 1.438
• CAS DataBase Reference: (hexyloxy)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (hexyloxy)acetic acid(57931-25-6)
• EPA Substance Registry System: (hexyloxy)acetic acid(57931-25-6)

Safety Data

• Hazardous Substances Data: 57931-25-6(Hazardous Substances Data)

Usage

General Description

(Hexyloxy)acetic acid, also known as 2-(hexyloxy)acetic acid, is a chemical compound with the molecular formula C10H20O3. It is an organic compound with a six-carbon hexyl chain attached to a carboxylic acid group. (hexyloxy)acetic acid is often used as a building block in the synthesis of pharmaceuticals and other organic compounds. It has potential applications in the production of drugs, fragrances, and other industrial products. (Hexyloxy)acetic acid is also used as a reagent in chemical reactions and as a starting material for the synthesis of various derivatives. It is important to handle this chemical with care, as it can be corrosive and hazardous if not properly handled.

InChI:InChI=1/C8H16O3/c1-2-3-4-5-6-11-7-8(9)10/h2-7H2,1H3,(H,9,10)

Upstream product

• 105-36-2 ethyl bromoacetate 
• 111-27-3 hexan-1-ol 
• 112-25-4 2-hexyloxyethanol 
• 3926-62-3 sodium monochloroacetic acid 
• 79-08-3 bromoacetic acid 
• 79-11-8 chloroacetic acid 

Downstream Products

• 1313867-85-4 C₂₂H₃₆N₂O₄ 
• 1313867-91-2 C₄₆H₆₄N₂O₈ 
• 1313867-90-1 C₄₉H₇₂N₂O₈Si 
• 1313867-88-7 C₂₉H₄₄N₂O₄Si 
• 1313867-87-6 C₃₂H₅₂N₂O₄Si₂ 
• 1313867-86-5 C₂₂H₃₄Br₂N₂O₄ 
• 112-58-3 dihexyl ether 
• 66675-06-7 1-(methoxymethoxy)hexane 
• 74231-58-6 7,10-dioxahexadecane 
• 70038-38-9 n-Hexyloxyessigsaeure-methylester 

Relevant articles and documents

Method for preparing acid through oxidating alcohols or aldehydes by oxygen

The invention provides a method for preparing acid through oxidating alcohols or aldehydes by using oxygen or oxygen in air as an oxidant. The method comprises the steps: oxidating the alcohols or aldehydes to produce the acid at room temperature in an organic solvent in a manner of taking ferric nitrate (Fe(NO3)3.9H2O), 2,2,6,6-tetramethylpiperidyl nitrogen oxide (TEMPO) and an inorganic halide as catalysts and taking the oxygen or air as an oxidant, and oxidating diols to produce lactone; or, carrying out a reaction on the aldehydes, which serve as a raw material, under neutral conditions by taking ferric nitrate as a catalyst, and oxidating the aldehydes to produce the acid and peroxy acid. The method has the advantages that the method is environmentally friendly, the cost is low, the yield is high, the atomic economical efficiency is high, the compatibility of substrate functional groups is good, the reaction conditions are mild, a reaction scale can be enlarged, and the like, so that the method is suitable for being applied to industrial production.

Design and synthesis of new vancomycin derivatives

A set of vancomycin derivatives with lipid chain attached via a glyceric acid linker was designed and synthesized. A concise synthesis towards these derivatives was developed and the IC50s of these new lipoglycopeptides were tested. Some of them showed very potent activity against both vancomycin sensitive and resistant strains.

Influences on the Selectivity of the Kolbe versus the Non-Kolbe Electrolysis in the Anodic Decarboxylation of Carboxylic Acids

The anodic decarboxylation of 3-oxanonanoic acid (2a) and 3-oxapentadecanoic acid (2b) in methanol leads exclusively to products of the non-Kolbe electrolysis.The influence of coelectrolysis, solvent, current density, degree of neutralization and chain length of the alkoxy group on the anodic decarboxylation of 2a, b have been investigated.An extended alkyl chain in the alkoxy group, coelectrolysis with long-chain fatty acids, ethanol or dimethylformamide as solvent, and a high current density favor the Kolbe coupling against the non-Kolbe electrolysis.Key Words: Kolbe electrolysis/ Non-Kolbe electrolysis/ Carboxylic acids, α-alkoxy-/ Solvent effects