57934-86-8

Upstream product

• 75-16-1 methylmagnesium bromide 
• 57782-64-6 6-methyl-5-[2-(2-methyl-[1,3]dioxolan-2-yl)-ethyl]-hept-3t-en-2-one 
• 60796-62-5 (+/-)-(E)-8,8-ethylenedioxy-5-isopropyl-2-methylnon-3-en-2-ol 
• 78-94-4 methyl vinyl ketone 
• 64932-36-1 2-bromo-3-methyl-butyraldehyde 
• 129777-25-9 (+/-)-(E)-9,9-ethylenedioxy-3-hydroxy-6-isopropyl-3-methyldec-4-enoic acid 
• 154870-27-6 ethyl 4-bromo-5-methyl-2-hexenoate 

Downstream Products

• 54868-48-3 (E)-5-isopropyl-8-methylnona-6,8-dien-2-one 

Relevant academic research and scientific papers

Ultrasound promoted synthesis of (±)-8-hydroxy-5-isopropyl-8-methyl- 6(E)-nonen-2-one ((±)-solanone hydrate) and 3,7-dimethyl-2(E),7- octadienylpropionate

A facile synthesis of the title compounds has been accomplished using Zn-Cu couple catalyzed conjugate addition of allylic halides to α,β- unsaturated ketones initiated by ultrasonic waves under aqueous conditions and Horner-Wittig reaction using ethyl α-dimethylphosphonoacetate and NaH as base in dry THF as the key steps in overall good yields.

Tobacco Chemistry. 70. Six New Cembrane-Derived Compounds from Tobacco

Six new compounds of probable cenbrane origin have been isolated from Greek tobacco.They have been identified as (E)-5-hydroxy-5-isopropylhept-3-en-2-one (1), (E)-4-isopropyl-7-oxooct-5-en-4-olide (2), (2E,6E)-5-isopropyl-2-methyl-8-oxonona-2,6-dienal (3), (E)-4-hydroxy-7-isopropyl-4-methylundec-5-ene-2,10-dione (4), (E)-3-hydroxy-6-isopropyl-3-methyl-9-oxodec-4-enoic acid (5) and (3E,7E)-6-hydroxy-9-isopropyl-6-methyltrideca-3,7-diene-2,12-dione (6) by spectral methods and synthesis (1, 2, 4-6).The biogenesis of 1-6 is discussed.

Flavoring and perfuming ingredients

Various compounds are disclosed to be useful in the flavoring of foodstuffs, animal feeds, beverages, pharmaceutical preparations and tobacco products. These compounds are equally useful perfuming ingredients.