57941-70-5Relevant articles and documents
Production device and method of high-content cyclic Grifola ester synthetic perfume (by machine translation)
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Paragraph 0040-0043, (2020/01/25)
The invention discloses a production device of high-content cyadoop synthetic perfume and a method for, producing the cyclohexyloxy acetic acid through the saponification, and O - H acidification of, the high-content cyclic Grifola (, cyclohexanone). (by machine translation)
Method for synthesizing high-content galbanum oxyacetate fragrance
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Paragraph 0040; 0042; 0049; 0051, (2019/12/25)
The invention discloses a method for synthesizing a high-content galbanum oxyacetate fragrance. The method replaces the Williamson reaction, and includes perform an O-H insertion reaction of ethyl diazoacetate and cyclohexanol under catalysis of a catalyst Rh2(OAc)4 to obtain ethyl cyclohexyloxyacetate, saponifying and acidifying to obtain cyclohexyloxyacetic acid, and esterifying with allyl alcohol to obtain galbanum oxyacetate. The method can greatly shorten the reaction time. In addition, a prepared solid acid catalyst Yb-MoO3/Al2O3-ZrO2 has the advantages of easy separation from a liquid phase reaction system, no corrosion on equipment and simple post-treatment, which overcomes the problems of corrosion of the existing liquid acid on the equipment and pollution of acid-containing wastewater on the environment; the catalyst has high selectivity, and can be applied at low temperatures, so as to save energy consumption, reduce occurrence of side reactions, and can greatly improve production efficiency, and the content of the prepared galbanum oxyacetate fragrance is as high as 99.6%; and the catalyst is good in thermal stability, and active components are not easy to lose, so thecatalyst has good reusability and is a new green catalytic material with great application potentials.
Nitrogenous Heterocyclic Derivatives And Their Application In Drugs
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Paragraph 0861, (2015/03/31)
The present invention relates to the field of medicine, provided herein are novel nitrogenous heterocyclic compounds, their preparation methods and their uses as drugs, especially for treatment and prevention of tissue fibrosis. Also provided herein are pharmaceutically acceptable compositions comprising the nitrogenous heterocyclic compounds and the uses of the compositions in the treatment of human or animal tissue fibrosis, especially for human or animal renal interstitial fibrosis, glomerular sclerosis, liver fibrosis, pulmonary fibrosis, peritoneal fibrosis, myocardial fibrosis, dermatofibrosis, postsurgical adhesion, benign prostatic hyperplasia, skeletal muscle fibrosis, scleroderma, multiple sclerosis, pancreatic fibrosis, cirrhosis, myosarcoma, neurofibroma, pulmonary interstitial fibrosis, diabetic nephropathy, alzheimer disease or vascular fibrosis.