579476-25-8

Basic information

• Product Name: 3-pyrimidin-2-yl benzoic acid methyl ester
• Synonyms: 3-pyrimidin-2-yl benzoic acid methyl ester
• CAS NO: 579476-25-8
• Molecular Weight: 214.224
• Mol File: 579476-25-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-pyrimidin-2-yl benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-pyrimidin-2-yl benzoic acid methyl ester(579476-25-8)
• EPA Substance Registry System: 3-pyrimidin-2-yl benzoic acid methyl ester(579476-25-8)

Safety Data

• Hazardous Substances Data: 579476-25-8(Hazardous Substances Data)

Upstream product

• 1722-12-9 2-chloropyrimidine 
• 2905-65-9 methyl 3-chlorobenzoate 
• 67-56-1 methanol 
• 7431-45-0 2-phenylpyrimidine 
• 558-13-4 carbon tetrabromide 
• 263349-22-0 3-(pyrimidin-2-yl)benzaldehyde 
• 74-88-4 methyl iodide 

Relevant articles and documents

Ruthenium-Catalyzed meta-Selective CAr-H Bond Formylation of Arenes

The meta-CAr-H bond formylation of arenes has been achieved using CHBr3 as a formyl source in the presence of [Ru(p-cym)(OAc)2] as a catalyst. This method provides efficient access to the preparation of various meta-substituted aromatic compounds, such as alcohols, ethers, amines, nitriles, alkenes, halogens, carboxylic acids, and their derivatives, through transformation of the versatile formyl group. Furthermore, mechanistic studies show that the key active species is a pentagonal ruthenacycle complex.

Cobalt-catalyzed cross-coupling between in situ prepared arylzinc halides and 2-chloropyrimidine or 2-chloropyrazine

A cobalt-catalyzed cross-coupling of aryl halides with 2-chloropyrimidines or 2-chloropyrazines is reported in satisfactory to high yields. The key step of this procedure is the formation of aromatic organozinc reagents and their coupling with 2-chlorodia