57968-81-7

Basic information

• Product Name: (+)-5-trans Cloprostenol
• Synonyms: (+)-5-trans Cloprostenol;[1R-[1alpha(E),2beta(1E,3R*),3alpha,5alpha]]-7-[2-[4-(3-Chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-5-Heptenoic acid;5,6-trans-cloprosten
• CAS NO: 57968-81-7
• Molecular Formula: C₂₂H₂₉ClO₆
• Molecular Weight: 424.91506
• Mol File: 57968-81-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (+)-5-trans Cloprostenol(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-5-trans Cloprostenol(57968-81-7)
• EPA Substance Registry System: (+)-5-trans Cloprostenol(57968-81-7)

Safety Data

• Hazardous Substances Data: 57968-81-7(Hazardous Substances Data)

Usage

Uses

(+)-(5)-trans Cloprostenol is an isomer of cloprostenol(C587300). Cloprostenol is an aryl-oxymethyl analog of prostaglandin F2α.

Upstream product

• 53872-62-1 [3aα,4α(E),5β,6aα]-(+/-)-4-[4-(3-chlorophenoxy)-3-oxo-1-butenyl]-hexahydro-5-hydroxy-2H-cyclopenta[b]-furan-2-one 
• 41723-91-5 4-carboxybutyliden triphenylphosphorane sodium 

Downstream Products

• 206555-98-8 cloprostenol 
• 54276-21-0 (+)-cloprostenol 

Relevant articles and documents

Synthesis of (±) travoprost and its analogs

A new synthetic approach for the antiglaucoma agent, travoprost (1) has been developed in four steps from key intermediate (2). Key transformations include Horner-Wadsworth-Emmons reaction and separation of diastereomers to obtain (±) travoprost (1) and its analogs.