58085-73-7

Basic information

• Product Name: 2-hydroxy-5-nonylbenzophenone
• Synonyms: 2-hydroxy-5-nonylbenzophenone;2-Hydroxy-5-nonylphenyl(phenyl) ketone;5-Nonyl-2-hydroxybenzophenone;Einecs 261-105-7;Methanone, (2-hydroxy-5-nonylphenyl)phenyl-
• CAS NO: 58085-73-7
• Molecular Formula: C₂₂H₂₈O₂
• Molecular Weight: 324.45652
• EINECS: 261-105-7
• Mol File: 58085-73-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 450.9°Cat760mmHg
• Flash Point: 192.1°C
• Appearance: /
• Density: 1.032g/cm³
• Vapor Pressure: 9.5E-09mmHg at 25°C
• Refractive Index: 1.548
• CAS DataBase Reference: 2-hydroxy-5-nonylbenzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-5-nonylbenzophenone(58085-73-7)
• EPA Substance Registry System: 2-hydroxy-5-nonylbenzophenone(58085-73-7)

Safety Data

• Hazardous Substances Data: 58085-73-7(Hazardous Substances Data)

Usage

Preparation

Preparation by Fries rearrangement of p-nonylphenyl benzoate with aluminium chloride, without solvent at 140–145° for 30–50 min (52%).

InChI:InChI=1/C22H28O2/c1-2-3-4-5-6-7-9-12-18-15-16-21(23)20(17-18)22(24)19-13-10-8-11-14-19/h8,10-11,13-17,23H,2-7,9,12H2,1H3

Synthetic route

4-Nonylphenol (104-40-5) + Benzotrichlorid (98-07-7) → 2-hydroxy-5-nonylbenzophenone (58085-73-7)

Conditions	Yield
With sodium hydroxide In water at 75 - 80℃; for 2.5h;	42%

2-hydroxy-5-nonylbenzophenone (58085-73-7) + methyl iodide (74-88-4) → 2-methoxy-5-nonyl benzophenone

Conditions	Yield
With sodium hydroxide; tetrabutylammomium bromide In dichloromethane; water; Petroleum ether	85%

1-Bromopentane (110-53-2) + 2-hydroxy-5-nonylbenzophenone (58085-73-7) → 2-n-pentoxy-5-nonyl benzophenone

Conditions	Yield
With sodium hydroxide; ammonium bromide In dichloromethane; water; Petroleum ether	82%

2-hydroxy-5-nonylbenzophenone (58085-73-7) → 2-hydroxy-5-nonylbenzophenone oxime (59986-58-2) + (2-Hydroxy-5-nonyl-phenyl)-phenyl-methanone oxime (59986-54-8)

Conditions	Yield
With potassium hydroxide; hydroxylamine hydrochloride In methanol for 8h;	A 78% B n/a
With sodium hydroxide; hydroxylamine hydrochloride In methanol for 1h; Heating;	A n/a B 55%

2-hydroxy-5-nonylbenzophenone (58085-73-7) + tetrabutylammomium bromide (1643-19-2) + isopropyl bromide (75-26-3) → 2-isopropoxy-5-nonyl benzophenone

Conditions	Yield
With sodium hydroxide In dichloromethane; water

Upstream product

• 104-40-5 4-Nonylphenol 
• 98-07-7 Benzotrichlorid 

Downstream Products

• 59986-58-2 2-hydroxy-5-nonylbenzophenone oxime 
• 59986-54-8 (2-Hydroxy-5-nonyl-phenyl)-phenyl-methanone oxime 

Relevant articles and documents

Synthesis and Spectral Data of (E) and (Z) Oximes of 2-Hydroxybenzophenone Derivatives

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