58089-74-0Relevant academic research and scientific papers
Rh-catalyzed allylic C-F bond activation: The stereoselective synthesis of trisubstituted monofluoroalkenes and a mechanism study
Zhang, He,Lin, Jin-Hong,Xiao, Ji-Chang,Gu, Yu-Cheng
, p. 581 - 588 (2014/01/06)
Rhodium-catalyzed allylic C-F bond activation via oxidative addition was found to be a promising approach for the conversion of allylic difluoro-homoallylic alcohols into trisubstituted monofluoroalkenes in good yields with excellent stereoselectivity. The mechanism study shows that C-F bond activation via oxidative addition is involved and PPh3 is responsible for the excellent stereoselectivity. The Royal Society of Chemistry.
