85864-61-5

Basic information

• Product Name: Benzenemethanol, a-(1,1-difluoro-2-propenyl)-
• CAS NO: 85864-61-5
• Molecular Formula: C10H10F2O
• Molecular Weight: 184.186
• Mol File: 85864-61-5.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-(1,1-difluoro-2-propenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-(1,1-difluoro-2-propenyl)-(85864-61-5)
• EPA Substance Registry System: Benzenemethanol, a-(1,1-difluoro-2-propenyl)-(85864-61-5)

Safety Data

• Hazardous Substances Data: 85864-61-5(Hazardous Substances Data)

Upstream product

• 1616058-75-3 2,2-difluoro-2-iodo-1-phenylethan-1-ol 
• 1401998-89-7 diisopropyl (3,3-difluoroallyl)boronate 
• 100-52-7 benzaldehyde 
• 219503-58-9 1,1,3-tribromo-3,3-difluoro-1-propene 
• 88257-92-5 1,1-difluoro-3-(dimethylphenylsilyl)propene 
• 64545-26-2 3,3-difluoro-3-(dimethylphenylsilyl)propene 
• 420-90-6 3-bromo-3,3-difluropropene 
• 109-72-8 n-butyllithium 

Downstream Products

• 1219978-47-8 (Z)-4-(diethylamino)-2-fluoro-1-phenylbut-2-en-1-ol 
• 1219978-46-7 (Z)-4-(benzyl(methyl)amino)-2-fluoro-1-phenylbut-2-en-1-ol 
• 1219978-48-9 (Z)-4-(3,3-difluoropyrrolidin-1-yl)-2-fluoro-1-phenylbut-2-en-1-ol 
• 1310740-09-0 (Z)-2-fluoro-1-phenylpent-2-en-1-ol 
• 1310740-10-3 (Z)-2-fluoro-1-phenylhex-2-en-1-ol 
• 6052-63-7 2-phenylbut-3-en-1-ol 
• 1310740-11-4 (Z)-2-fluoro-6-methyl-1-phenylhept-2-en-1-ol 
• 1310740-26-1 tert-butyl(2,2-difluoro-1-phenylbut-2-enyloxy)dimethylsilane 
• 1310740-27-2 (Z)-tert-butyl(2-fluoro-1-phenylhex-2-enyloxy)dimethylsilane 
• 1314358-02-5 (1R,3S)-2,2-difluoro-1-phenylbutane-1,3-diol 
• 58089-74-0 (Z)-2-fluoro-1-phenylbut-2-en-1-one 

Relevant articles and documents

Vinylation of Iododifluoromethylated Alcohols via a Light-Promoted Intramolecular Atom-Transfer Reaction

A method for the synthesis of gem -difluorohomoallylic alcohols by the substitution of iodine in the iododifluoromethyl group by a vinyl fragment is described. The reaction proceeds via an intramolecular iodine atom transfer followed by β-elimination. The reaction is performed in the presence of an iridium photocatalyst, fac -Ir(ppy) 3, and triphenylphosphine under irradiation with light-emitting diodes.

Rh-catalyzed allylic C-F bond activation: The stereoselective synthesis of trisubstituted monofluoroalkenes and a mechanism study

Rhodium-catalyzed allylic C-F bond activation via oxidative addition was found to be a promising approach for the conversion of allylic difluoro-homoallylic alcohols into trisubstituted monofluoroalkenes in good yields with excellent stereoselectivity. The mechanism study shows that C-F bond activation via oxidative addition is involved and PPh3 is responsible for the excellent stereoselectivity. The Royal Society of Chemistry.

B -(3,3-Difluoroallyl)diisopinocampheylborane for the enantioselective fluoroallylboration of aldehydes

The fluoroallylboration of aldehydes with B-(3,3-difluoroallyl) diisopinocampheylborane, which was prepared via the hydroboration of 1,1-difluoroallene, provides chiral 2,2-gem-difluorinated homoallylic alcohols in good yields and 91-97% ee.