581-00-0

Usage

Uses

Used in Pharmaceutical Industry:
2-methyl-4-morpholin-4-ylaniline is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the formation of complex organic molecules that can exhibit therapeutic properties.
Used in Dye Industry:
In the dye industry, 2-methyl-4-morpholin-4-ylaniline is utilized as an intermediate to produce dyes, taking advantage of its aromatic and amine characteristics to create a range of colorants for various applications.
Used in Agrochemical Production:
2-methyl-4-morpholin-4-ylaniline serves as a precursor in the production of various agrochemicals, where its chemical structure can be manipulated to create compounds that are effective in agricultural settings.
Used in Organic Synthesis as a Reagent:
As a reagent in organic synthesis, 2-methyl-4-morpholin-4-ylaniline is employed to facilitate specific chemical reactions, leveraging its functional groups to achieve desired outcomes in the synthesis of target compounds.

Upstream product

• 446-33-3 5-Fluoro-2-nitrotoluene 
• 220679-09-4 4-(3-methyl-4-nitrophenyl)morpholine 

Downstream Products

• 1395172-03-8 C₂₉H₄₀N₈O₄ 
• 1395172-00-5 C₂₇H₃₇N₇O₃ 
• 1246529-64-5 4-[(2-{[2-methyl-4-(morpholin-4-yl)phenyl]amino}-9H-purin-6-yl)amino]cyclohexanol 
• 1246529-35-0 ethyl 4-[(2-{[2-methyl-4-(morpholin-4-yl)phenyl]amino}-9H-purin-6-yl)amino]piperidine-1-caxboxylate 
• 1383810-38-5 C₂₁H₂₈N₈O 
• 1383810-36-3 C₂₀H₂₅N₇O₂ 
• 1395172-07-2 C₂₅H₃₃N₇O₃ 
• 1246529-78-1 6-(cyclohexyloxy)-N-[2-methyl-4-(morpholin-4-yl)phenyl]-9H-purin-2-amine 
• 1383810-33-0 C₂₃H₃₂N₈O 
• 1395172-17-4 C₃₁H₄₄N₈O₃ 
• 1246529-94-1 N₂-[2-methyl-4-(morpholin-4-yl)phenyl]-N₆-[4-(morpholin-4-yl)cyclohexyl]-9H-purine-2,6-diamine 
• 1246529-32-7 MPI-0479605 

Relevant academic research and scientific papers

A class of FLT3 kinase inhibitors, preparation and application thereof

The invention relates to a class of FLT3 kinase inhibitors, preparation and application thereof, wherein specifically the compound has a structure represented by a formula (I), and all groups and substituents are defined in the specification. The invention also discloses a preparation method of the compound, and application of the compound in inhibition of FLT3.

Quinoline derivative, and preparation method and uses thereof

The invention relates to a quinoline derivative, and a composition including the derivative, and also relates to a preparation method of the derivative, and uses of the derivative in the prevention ortreatment of harmful fungi and the killing of pests.

Lead optimization of purine based orally bioavailable Mps1 (TTK) inhibitors

Efforts to optimize biological activity, novelty, selectivity and oral bioavailability of Mps1 inhibitors, from a purine based lead MPI-0479605, are described in this Letter. Mps1 biochemical activity and cytotoxicity in HCT-116 cell line were improved. On-target activity confirmation via mechanism based G2/M escape assay was demonstrated. Physico-chemical and ADME properties were optimized to improve oral bioavailability in mouse.

QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Compounds of formula (I) are found to be active in inhibiting replication of flaviviridae viruses, R is C1-C4 alkyl or C1-C4 alkoxy.

MORPHOLINYLANILINOQUINAZO- LINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS

Compounds of formula (Ia) are found to be active in inhibiting replication of flaviviridae viruses, wherein R1, R2, R3 and R4 are as defined in the claims.