58110-34-2

Basic information

• Product Name: 58110-34-2
• Synonyms: 3-(5-(4-nitrophenyl)-2-furanyl)-2-propenoic acid;2-Propenoic acid, 3-[5-(4-nitrophenyl)-2-furanyl]-
• CAS NO: 58110-34-2
• Molecular Formula: C13 H9 N O5
• Molecular Weight: 0
• Mol File: 58110-34-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 58110-34-2(CAS DataBase Reference)
• NIST Chemistry Reference: 58110-34-2(58110-34-2)
• EPA Substance Registry System: 58110-34-2(58110-34-2)

Safety Data

• Hazardous Substances Data: 58110-34-2(Hazardous Substances Data)

Upstream product

• 141-82-2 malonic acid 
• 7147-77-5 5-(4-nitrophenyl)-2-furaldehyde 
• 127-09-3 sodium acetate 
• 938056-33-8 methyl (E)-3-[5-(4-nitrophenyl)-furan-2-yl]acrylate 
• 1899-24-7 5-bromo-2-furancarboxaldehyde 
• 24067-17-2 4-nitrophenylboronic acid 

Downstream Products

• 104431-32-5 2-(4-Nitrophenyl)-1-(5-(4-nitrophenyl)-2-furyl)ethylene 
• 179870-09-8 (E)-3-[5-(4-Nitro-phenyl)-furan-2-yl]-acryloyl azide 

Relevant articles and documents

Development of molecular probes for second-site screening and design of protein tyrosine phosphatase inhibitors

We report on the design, synthesis, and evaluation of a series of furanyl-salicyl-nitroxide derivatives as effective chemical probes for second-site screening against phosphotyrosine phosphatases (PTPs) using NMR-based techniques. The compounds have been

Synthesis of 2-arylfuro[3,2-c]pyridines and their derivatives

A series of 2-arylfuro[3,2-c]pyridines was synthesized. 3-(5-Aryl-2-furyl)propenoic acids 1a-1h were converted to the acid azides 2a-2h, which in turn were cyclized to give 2-arylfuro[3,2-c]pyridine-4(5H)-ones 4a-4h by heating in Dowtherm. The pyridones 4a-4f were aromatized with phosphorus oxychloride to the 2-aryl-4-chlorofuro[3,2-c]pyridines 5a-5f, which were reduced with zinc and acetic acid to the title compounds 6a-6f. Reacted with phosphorus(V) sulfide, the pyridones 4a-4f yielded the corresponding thiones 7a-7f.