58124-14-4 Usage
Type of compound
Flavonoid
Sources
Citrus fruits, parsley, chamomile
+ Antioxidant
Reduces oxidative stress in the body.
+ Anti-inflammatory
Decreases inflammation in the body.
+ Anticancer
Inhibits the growth of cancer cells and induces apoptosis in tumor cells.
Potential applications
+ Reducing the risk of chronic diseases such as cancer, cardiovascular disease, and diabetes.
+ Therapeutic applications in the treatment and prevention of various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 58124-14-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,1,2 and 4 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 58124-14:
(7*5)+(6*8)+(5*1)+(4*2)+(3*4)+(2*1)+(1*4)=114
114 % 10 = 4
So 58124-14-4 is a valid CAS Registry Number.
58124-14-4Relevant articles and documents
Inhibitory effect of flavonoids on human glutaminyl cyclase
Li, Manman,Dong, Yao,Yu, Xi,Zou, Yongdong,Zheng, Yizhi,Bu, Xianzhang,Quan, Junmin,He, Zhendan,Wu, Haiqiang
, p. 2280 - 2286 (2016/04/26)
Glutaminyl cyclase (QC) plays an important role in the pathogenesis of Alzheimer's disease (AD) and can be a potential target for the development of novel anti-AD agents. However, the study of QC inhibitors are still less. Here, phenol-4′ (R1-), C5-OH (R2-) and C7-OH (R3-) modified apigenin derivatives were synthesized as a new class of human QC (hQC) inhibitors. The efficacy investigation of these compounds was performed by spectrophotometric assessment and the structure-activity relationship (SAR) was evaluated. Molecular docking was also carried out to analyze the binding mode of the synthesized flavonoid to the active site of hQC.