72357-29-0

Upstream product

• 65612-84-2 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(2,4-dimethoxyphenyl)propane-1,3-dione 
• 58124-14-4 2-(2,4-dimethoxyphenyl)-5,7-dihydroxy-4H-chromen-4-one 
• 77-78-1 dimethyl sulfate 
• 142009-26-5 artocarpetin 
• 392302-12-4 2'-acetoxy-2,4,4',6'-tetramethoxy-chalcone 
• 392302-41-9 acetic acid 2-[2,3-dibromo-3-(2,4-dimethoxy-phenyl)-propionyl]-3,5-dimethoxy-phenyl ester 
• 90-24-4 2-hydroxy-4,6-dimethoxyacetophenone 
• 53931-00-3 2,4-dimethoxybenzoic anhydride 
• 76583-07-8 3-(2,4-dimethoxyphenyl)-1-(2-hydroxy-4,6-dimethoxyphenyl)prop-2-en-1-one 
• 2150-41-6 methyl 2, 4-dimethoxybenzoate 
• 392302-49-7 Acetic acid 2-[(Z)-2-bromo-3-(2,4-dimethoxy-phenyl)-acryloyl]-3,5-dimethoxy-phenyl ester 

Downstream Products

• 104777-82-4 5,7,2',4'-tetraacetoxyflavone 
• 520-30-9 norartocarpetin 

Relevant academic research and scientific papers

Solution phase synthesis of a combinatorial library of chalcones and flavones as potent cathepsin v inhibitors

Cathepsin V is a papain-like cysteine protease. It is involved in the control of human T cells (responsible for cell immunity), and presents the largest elastolytic activity among the proteolytic enzymes. Therefore, cathepsin V is a potential molecular ta

An environmentally benign synthesis of aurones and flavones from 2′-acetoxychalcones using n-tetrabutylammonium tribromide

A wide variety of aurones (3a-f) can be prepared exclusively from 2′-acetoxychalcones (1a-f) in high yields in two steps, by bromination using n-tetrabutylammonium tribromide (TBATB) in the presence of CaCO3 in CH2Cl2-MeOH (5:2) at 0-5°C followed by cyclization of the brominated products 2a-f on treating with 0.2 M ethanolic KOH solution at 0-5°C, respectively. In contrast various flavone derivatives 6a-f can be obtained exclusively from compounds 1a-f in fairly good yields, by brominating with the same reagent in CH2Cl2, followed by dehydrobromination and finally cyclization on treating with 0.1 M NaOMe solution.