58158-45-5

Basic information

• Product Name: 1-(4-CHLORO-PHENYL)-2-PYRIDIN-4-YL-ETHANONE
• Synonyms: 1-(4-CHLORO-PHENYL)-2-PYRIDIN-4-YL-ETHANONE;1-(4-Chlorophenyl)-2-(4-pyridinyl)-ethanone;Ethanone, 1-(4-chlorophenyl)-2-(4-pyridinyl)-
• CAS NO: 58158-45-5
• Molecular Formula: C₁₃H₁₀ClNO
• Molecular Weight: 231.68
• Mol File: 58158-45-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 395.229 °C at 760 mmHg
• Flash Point: 192.828 °C
• Appearance: /
• Density: 1.24 g/cm³
• CAS DataBase Reference: 1-(4-CHLORO-PHENYL)-2-PYRIDIN-4-YL-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-CHLORO-PHENYL)-2-PYRIDIN-4-YL-ETHANONE(58158-45-5)
• EPA Substance Registry System: 1-(4-CHLORO-PHENYL)-2-PYRIDIN-4-YL-ETHANONE(58158-45-5)

Safety Data

• Hazardous Substances Data: 58158-45-5(Hazardous Substances Data)

Usage

General Description

1-(4-CHLORO-PHENYL)-2-PYRIDIN-4-YL-ETHANONE is a chemical compound with the molecular formula C13H9ClNO. It belongs to the class of organic compounds known as pyridine carboxylic acids and derivatives. 1-(4-CHLORO-PHENYL)-2-PYRIDIN-4-YL-ETHANONE is characterized by a pyridyl substituent attached to a ketone group, as well as a 4-chloro phenyl group. It is commonly used in the synthesis of various pharmaceuticals, agrochemicals, and organic materials due to its versatile reactivity. Additionally, it has potential applications in medicinal chemistry and drug development due to its ability to modulate biological activities. The compound's chemical structure and properties make it an essential building block for the preparation of diverse molecular structures with potential therapeutic and industrial uses.

Upstream product

• 108-89-4 picoline 
• 623-03-0 4-Cyanochlorobenzene 
• 122334-37-6 4-chloro-N-methoxy-N-methylbenzamide 
• 26954-25-6 (4-pyridylmethyl)lithium 
• 122-01-0 4-chloro-benzoyl chloride 
• 21384-46-3 (4-chlorophenyl)(2-methylaziridin-1-yl)methanone 
• 13295-97-1 4-[2-(4-chlorophenyl)ethynyl]pyridine 

Downstream Products

• 902170-98-3 1-(4-chloro-phenyl)-2-pyridin-4-yl-ethane-1,2-dione 2-oxime 
• 861804-68-4 4-[5-(4-chloro-phenyl)-4-pyridin-4-yl-1H-pyrrol-2-yl]-piperidine-1-carboxylic acid benzyl ester 
• 224038-60-2 [4-(4-chlorophenyl)-5-(4-pyridyl)-1,3-thiazol-2-yl]amine 
• 271575-25-8 1-(4-chlorophenyl)-2-(1,3-dithietan-2-ylidene)-2-(4-pyridinyl)ethanone 
• 861804-92-4 4-[4-(4-chloro-phenyl)-4-oxo-3-pyridin-4-yl-butyryl]-piperidine-1-carboxylic acid benzyl ester 
• 125996-84-1 1-Benzyl-4-[2-(4-chloro-phenyl)-2-oxo-ethyl]-pyridinium; bromide 

Relevant articles and documents

Synthesis and biological activities of 4-phenyl-5-pyridyl-1,3-thiazole derivatives as selective adenosine A3 antagonists

To investigate the potency of an adenosine A3 receptor (A 3AR) antagonist as an anti-asthmatic drug, a novel series of 4-phenyl-5-pyridyl-1,3-thiazole derivatives was synthesized and evaluated in human adenosine A1, A

Triazolopyrimidine heterocycles as cannabinoid receptor modulators

The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents and methods of treatment using the compounds a

Adenosine A3 receptor antagonists

A pharmaceutical composition for antagonizing adenosine at adenosine A3receptors which comprises a 1,3-azole compound substituted on the 4- or 5-position, or both, by a pyridyl which may be substituted is provided and can be used as a prophylactic and therapeutic agent for asthma, allergosis, inflammation, and so on.