58185-54-9Relevant academic research and scientific papers
Polymer network formation using the phosphane-ene reaction: A thiol-ene analogue with diverse postpolymerization chemistry
Guterman, Ryan,Rabiee Kenaree, Amir,Gilroy, Joe B.,Gillies, Elizabeth R.,Ragogna, Paul J.
, p. 1412 - 1419 (2015)
Air-stable primary phosphines were photopolymerized using phosphane-ene chemistry, the phosphorus analogue of the thiol-ene reaction, to fabricate a completely new class of polymer networks. It was demonstrated that the tunable thermal and physical properties accessible using thiol-ene chemistry could also be achieved using an analogous phosphane-ene reaction. At the same time, the presence of the 31P nucleus that is easily observed using NMR spectroscopy allowed the chemical structures of the networks to be directly probed using solid state NMR spectroscopy. Following its incorporation into the network, phosphorus offers the distinct difference and advantage of being able to undergo a diverse array of further derivatization to afford functional materials. For example, the networks were demonstrated to serve as effective oxygen scavengers and to bind transition metals (e.g., Pd). By using the air stable ferrocenyl phosphine (FcCH2CH2)PH2, redox-active networks were produced and these materials could be pyrolyzed to yield magnetic ceramics. Overall, this demonstrates the promise of phosphane-ene chemistry as an alternative to thiol-ene systems for providing functional materials for a diverse range of applications.
Facile Synthesis of Hydroxy-Substituted Thiacrown Ethers via Nucleophilic Ring Opening of Epoxides
Stefaniak, Monika,Romański, Jaros?aw
, p. 2214 - 2220 (2019/05/10)
The title thiacrown ethers were prepared in a one-step procedure to give a series of unique macrocycles possessing two unsubstituted hydroxy groups that can be easily functionalized. In addition, epoxides and macrocycles derived from Cookson's birdcage diketone, were prepared. The nucleophilic ring opening of epoxides synthesis can be classified in the frame of click chemistry. Surprisingly, some of the prepared allyl substituted polyglycols as well as bis-epoxides, especially sulfur analogues, were prepared for the first time.
Application of HPLC for the screening of separation of new macrocyclic systems
Stefaniak, Monika,Romański, Jaros?aw
, p. 245 - 248 (2017/01/22)
The efficient synthesis of new macrocyclic systems via nucleophilic ring opening reaction of epoxides by thiols was described. Initially new macrocyclic compounds were obtained as a mixture of diastereomers. Preparative thin layer chromatography was applied to separate meso and pairs of enantiomer. The identification of products using a chiral HPLC column and mass spectroscopy was utilized.
Controlled-length efficient synthesis of heterobifunctionalized oligo ethylene glycols
Zona, Cristiano,D'Orazio, Giuseppe,La Ferla, Barbara
supporting information, p. 709 - 712 (2013/05/09)
A set of heterobifunctional oligo ethylene glycols have been synthesized in a straightforward and stepwise manner starting from inexpensive, commercially available, tetraethylene glycol. Introduction of terminal allyl moieties followed by reductive ozonolysis allowed controlled elongation. Mono-allyl derivatives were used for the elongation with a functionalized moiety and for successive introduction of different functional groups on the chain terminal. Georg Thieme Verlag Stuttgart - New York.
Phototriggering of cell adhesion by caged cyclic RGD peptides
Petersen, Svea,Alonso, Jose Maria,Specht, Alexandre,Duodu, Portia,Goeldner, Maurice,Del Campo, Aranzazu
, p. 3192 - 3195 (2008/12/23)
Restrained potential: A caged cyclic peptide attached to a surface is able to trigger cell attachment to the surface with spatiotemporal definition upon exposure to light (λ = 351 nm). The peptide shows no integrin-binding activity in its caged form, but mediates cell adhesion effectively after irradiation (see optical microscopy image of cells on a surface irradiated through a mask in bands 100 μm in width). (Figure Presented).
An expedient synthesis of monodispersed oligo(ethylene glycols)
Burkett, Brendan A.,Chan, Tak Hang
, p. 1007 - 1010 (2007/10/03)
A convenient approach to the synthesis of oligo(ethylene glycols) under phase transfer conditions is described. Oligo(ethylene glycols) (x = 7-12) are obtained in excellent yields and high purity via modular, bi-directional elongation of readily available ethylene glycol bis-tosylates.
Scope and limitations of ruthenium-catalyzed metathesis of simple polymer-bound alkenes
Breed,Ramsden,Brown
, p. 1049 - 1057 (2007/10/03)
Synthetic procedures for the preparation of two types of functional resin are described, both based on 2% cross-linked polystyrene with a high density (>60%) of side-chains and terminated by a primary alcohol. In the first case the C11 side-cha
