58200-88-7 Usage
Uses
Due to the limited information available on 6-amidino-2-naphthol, it is difficult to provide a comprehensive list of its applications. However, based on the general properties of naphthols and amidine-containing compounds, it can be inferred that 6-amidino-2-naphthol may have potential uses in the following areas:
Used in Chemical Research:
6-amidino-2-naphthol is used as a research compound for studying the properties and potential applications of naphthol and amidine-containing compounds.
Used in Pharmaceutical Development:
6-amidino-2-naphthol is used as a starting material or intermediate in the synthesis of pharmaceutical compounds, given its structural features that may be of interest in drug design.
Used in Material Science:
6-amidino-2-naphthol is used as a component in the development of new materials, such as dyes, pigments, or polymers, due to its chemical structure and potential reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 58200-88-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,2,0 and 0 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 58200-88:
(7*5)+(6*8)+(5*2)+(4*0)+(3*0)+(2*8)+(1*8)=117
117 % 10 = 7
So 58200-88-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H10N2O/c12-11(13)9-2-1-8-6-10(14)4-3-7(8)5-9/h1-6H,12-13H2
58200-88-7Relevant academic research and scientific papers
Inhibition of the tissue factor/factor VIIa complex - Lead optimisation using combinatorial chemistry
Roussel, Patrick,Bradley, Mark,Kane, Peter,Bailey, Christine,Arnold, Ruth,Cross, Andrew
, p. 6219 - 6230 (2007/10/03)
Following a high throughput screen (HTS) for the inhibition of the tissue factor/factor VIIa complex and the identification of a number of original hits a lead optimisation programme was initiated to improve their potency. This necessitated the development of an amidine based linker which allowed the generation of a library of amidinonaphthols prepared both by multiple parallel synthesis (MPS) and split and mix methods. The most active compound had an IC50 of 4μM some 10x more potent than the original lead compound.
