58207-08-2

Upstream product

• 27151-57-1 4-methoxy-N-(4-methoxyphenyl)-N-methylaniline 
• 4363-35-3 Dihydroxy-styryl-boran 
• 298-12-4 Glyoxilic acid 
• 208927-49-5 2-(Benzhydrylidene-amino)-4-fluoro-4-phenyl-butyric acid ethyl ester 
• 1786-36-3 (2-bromo-1-fluoroethyl)benzene 

Relevant academic research and scientific papers

Method for the synthesis of amines and amino acids with organoboron derivatives

Amines and amino acids are prepared by reacting an amine, a carbonyl derivative, and an organoboron compound under mild conditions.

Synthesis of γ-fluoro-α-methyl-α-amino acids. A new alkylation procedure for ester imines

Deprotonation of alanine ester imines with KO'Bu in DMSO or DMF and alkylation of the formed enolates with several 2-fluoroalkyl halogenides 2 and subsequent hydrolysis of the imino and the ester groups are presented as an efficient three-step sequence for the synthesis of racemic title compounds 5.