58219-53-7

Basic information

• Product Name: Methyl 3-methoxy-3-phenylbutanoate
• Synonyms: Methyl 3-methoxy-3-phenylbutanoate
• CAS NO: 58219-53-7
• Molecular Weight: 208.257
• Mol File: 58219-53-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Methyl 3-methoxy-3-phenylbutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 3-methoxy-3-phenylbutanoate(58219-53-7)
• EPA Substance Registry System: Methyl 3-methoxy-3-phenylbutanoate(58219-53-7)

Safety Data

• Hazardous Substances Data: 58219-53-7(Hazardous Substances Data)

Upstream product

• 107-31-3 Methyl formate 
• 98-83-9 isopropenylbenzene 
• 811-98-3 d⁽⁴⁾-methanol 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 

Downstream Products

• 3461-50-5 methyl trans-3-methylcinnamate 

Relevant articles and documents

Visible-Light-Driven, Metal-Free Divergent Difunctionalization of Alkenes Using Alkyl Formates

In recent decades, difunctionalization of alkenes has received considerable attention as an efficient and straightforward way to increase molecular complexity. However, examples of the difunctionalization of alkenes initiated by the intermolecular addition of alkoxycarbonyl radicals providing substituted alkanoates are still rare. Herein, we present the visible light-driven metal-free divergent difunctionalization of alkenes triggered by the intermolecular addition of alkoxycarbonyl radicals under ambient conditions. Employing alkyl formates as precursors of alkoxycarbonyl radicals and 4CzIPN as the photocatalyst, a variety of substituted alkanoates, including β-alkoxy, β-hydroxy, β-dimethoxymethoxy, and β-formyloxy alkanoates, could be facilely accessed with high functional group tolerance and high efficiency. Moreover, the mechanism study revealed that β-hydroxy alkanoates were generated by a selective decomposition of orthoformates promoted by the N-alkoxyazinium salt.

Electron Transfer Profile of Cyclopropanone Acetals in the Nonirradiated Reaction with Tetracyanoethylene, Chloranil, and Dicyanodichlorobenzoquinone

The donor profiles of cyclopropanone acetals 1 and 2 were examined in the reactions with electron acceptors (TCNE, DDQ, chloranil, and 1-cyanonaphthalene).With TCNE under nonirradiating conditions, an exclusive 2 + 2 cycloaddition took place stereospecifically with monosubstituted acetals 1a-c but nonstereospecifically with disubstituted acetals 1d,e.With quinones, a ring-opening of the cyclopropane and its coupling with the quinone took place to give the C (cyclopropane)-O (quinone) adduct 9 (with chloranil) or 10 (with DDQ), the latter of which underwent the elimination of a phenol to produce unsaturated esters 5 and 6.In addition, the intervention of the C (cyclopropane)-C (quinone) adduct 14 (with chloranil) or 15 (with DDQ), both as the precursor of 5 and 6, was also postulated.With 1-cyanonaphthalene, under photolysis, the cis/trans isomerization of 1 and 2 occured.The results provided evidences that cyclopropanone acetals, in general, are prone to function as donors.The mechanism of the reaction with quinones, in particular, was investigated in detail.