582321-75-3

Upstream product

• 69739-34-0 t-butyldimethylsiyl triflate 
• 582321-74-2 (S)-Pyrrolidine-1,2-dicarboxylic acid 2-((1S,3S,5S,6S,8R)-8-benzoyloxy-1-tert-butyl-5-hydroxy-3,6-dimethyl-7-oxo-nonyl) ester 1-tert-butyl ester 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 676324-77-9 (3R,5S)-5-(4-methoxybenzyloxy)-3,6,6-trimethylheptanal 
• 582321-71-9 pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-[1-tert-butyl-5-(tert-butyl-dimethyl-silanyloxy)-3-methyl-pentyl] ester 
• 582321-73-1 pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-(1-tert-butyl-3-methyl-5-oxo-pentyl) ester 
• 582321-70-8 (3S,5S)-7-(tert-Butyl-dimethyl-silanyloxy)-2,2,5-trimethyl-heptan-3-ol 
• 582321-69-5 (S)-acrylic acid 1-tert-butyl-but-3-enyl ester 
• 582321-91-3 (S)-6-(tert-butyl)-5,6-dihydro-2H-pyran-2-one 
• 531559-40-7 (4R,6S)-6-tert-butyl-4-methyltetrahydro-2H-pyran-2-one 
• 67760-86-5 (3S)-2,2-dimethyl-5-hexen-3-ol 
• 676324-76-8 (3S,5S)-5-(4-methoxybenzyloxy)-3,6,6-trimethylheptan-1-ol 
• 197454-20-9 (S)-5,5-dimethyl-4-hydroxyhexan-2-one 
• 878626-78-9 (1R,3S,4S,6S,8S)-4-(tert-butyldimethylsilyloxy)-8-(4-methoxybenzyloxy)-1,3,6,9,9-pentamethyl-2-oxodecyl benzoate 

Downstream Products

• 878626-88-1 (S)-Pyrrolidine-1,2-dicarboxylic acid 2-[(1S,3S,5S,6S)-6-((E)-(S)-3-allyloxycarbonyl-1-tritylsulfanylmethyl-but-2-enylcarbamoyl)-1-tert-butyl-5-hydroxy-3-methyl-heptyl] ester 1-tert-butyl ester 
• 878626-80-3 (S)-Pyrrolidine-1,2-dicarboxylic acid 2-[(1S,3R,5S,6S)-6-((E)-(S)-3-allyloxycarbonyl-1-tritylsulfanylmethyl-but-2-enylcarbamoyl)-1-tert-butyl-5-(tert-butyl-dimethyl-silanyloxy)-3-methyl-heptyl] ester 1-tert-butyl ester 
• 878626-86-9 pyrrolidine-2-carboxylic acid 1-tert-butyl-6-(4-{2-[1-({1-[(1-carboxy-2-methyl-butyl)-methyl-carbamoyl]-ethyl}-methyl-carbamoyl)-2-(4-methoxy-phenyl)-ethylcarbamoyl]-propenyl}-4,5-dihydro-thiazol-2-yl)-5-hydroxy-3-methyl-heptyl ester 
• 878626-89-2 (S)-Pyrrolidine-1,2-dicarboxylic acid 2-[(1S,3S,5S,6S)-6-((E)-(S)-3-allyloxycarbonyl-1-tritylsulfanylmethyl-but-2-enylcarbamoyl)-1-tert-butyl-5-hydroxy-3-methyl-heptyl] ester 1-(9H-fluoren-9-ylmethyl) ester 
• 878626-72-3 1-[(9H-fluoren-9-yl)methyl] 2-[(3S,5S,7S,8S)-9-{[(S,E)-5-(allyloxy)-4-methyl-5-oxo-1-(tritylthio)pent-3-en-2-yl]amino}-2,2,5,8-tetramethyl-9-oxo-7-{[(2,2,2-trichloroethoxy)carbonyl]oxy}nonan-3-yl] (S)-pyrrolidine-1,2-dicarboxylate 
• 878626-85-8 1-[(9H-fluoren-9-yl)methyl] 2-[(3S,5S,7S,8S)-8-({S}-4-{[5S,8S,11S,E]-11-[(S)-sec-butyl]-5-[4-methoxybenzyl]-2,7,8,10-tetramethyl-3,6,9,12-tetraoxo-13-oxa-4,7,10-triazahexadeca-1,15-dien-1-yl}-4,5-dihydrothiazol-2-yl)-7-hydroxy-2,2,5-trimethylnonan-3-yl] (S)-pyrrolidine-1,2-dicarboxylate 
• 350791-64-9 (-)-apratoxin A 
• 582321-88-8 (E)-(2S,3S,5R,7S,10S,16S,19S,22S,27S)-16-((S)-sec-Butyl)-7-tert-butyl-22-(4-methoxy-benzyl)-2,5,17,19,20,25-hexamethyl-3-triethylsilanyloxy-8-oxa-29-thia-14,17,20,23,30-pentaaza-tricyclo[25.2.1.0^10,14]triaconta-1⁽³⁰⁾,25-diene-9,15,18,21,24-pentaone 
• 582321-87-7 pyrrolidine-2-carboxylic acid 1-tert-butyl-6-(4-{2-[1-({1-[(1-carboxy-2-methyl-butyl)-methyl-carbamoyl]-ethyl}-methyl-carbamoyl)-2-(4-methoxy-phenyl)-ethylcarbamoyl]-propenyl}-4,5-dihydro-thiazol-2-yl)-3-methyl-5-triethylsilanyloxy-heptyl ester 
• 582321-86-6 C₅₂H₈₇N₅O₉SSi 
• 582321-83-3 C₅₇H₉₆N₄O₁₃SSi 
• 582321-85-5 C₅₇H₉₅N₅O₁₁SSi 
• 582321-84-4 C₅₇H₉₅N₇O₁₂SSi 
• 582321-66-2 C₅₇H₉₅N₇O₁₂SSi 

Relevant academic research and scientific papers

Total synthesis of apratoxin A

We have achieved a total synthesis of apratoxin A in which thiazoline formation was accomplished from the moCys containing amide 4 using PPh 3(O)/Tf2O. Deprotection of the Troc and allyl ester in 17, coupling with tripeptide 3, and d

Total synthesis of apratoxin A

Apratoxin A, a cyclodepsipeptide isolated from cyanobacterial Lyngbya spp, has been synthesized. The total synthesis features stereocontrolled access to the novel polyketide and the late-stage installation of the sensitive 2,4-disubstituted thiazoline moi